The link below to an article in MedScape brings forward some important considerations on the use of marijuana for both medical and recreational use.
A few years ago I looked into obtaining medical cannabis with low THC and high CBD but at that time found it VERY difficult to find a reliable grower. Apparently CBD oil is now legal in most states as it is derived from the commercial hemp plant. According to the article, which is written by a research PhD, CBD has been proven to be VERY safe, as opposed to cannabis with high THC content. He also references the bortezomib and CBD study.
Best,
Steve
Michael E. Schatman, "Medical Marijuana: The State of the Science," Medscape, Feb 6, 2015.
Summary:
Medical cannabinoids are here to stay, but intellectual honesty is imperative if we are moving toward exploiting their potential benefits. Owing to rising THC concentrations of products, "medical" marijuana is rarely good medicine. This review has identified the dangers associated with whole-plant marijuana, whether used for recreational or for supposedly medical purposes.
CBD, on the other hand, has a rich and expanding body of empirical support for safety, and more recently, for clinical efficacy in the treatment of numerous refractory conditions. However, it is premature to consider CBD a panacea for all that ails our patients. With legislative changes, access to CBD for both experimental and clinical use will become progressively less complicated, which should result in the publication of high-quality research of its efficacy and safety.
In addition, ease of access should help us better comprehend such issues as ideal routes of administration and dosing. With the facilitation of access to CBD that we are witnessing, in conjunction with problems associated with medical marijuana dispensary systems, is there any reason to not dismantle the dispensary systems as they currently exist? Recreational marijuana is a completely separate issue, and we owe it to our patients—as well as to society as a whole—to make sure that these entities are not joined. Only such a "separation of church and state" will result in unlocking of some of the mysteries surrounding medical cannabinoids, thereby allowing us to increase our treatment armamentaria.
Forums
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Steve - Name: Steve
- Who do you know with myeloma?: myself
- When were you/they diagnosed?: December 2009
- Age at diagnosis: 55
Re: Medical Cannabis Treatments?
Well there it is then. No need to question it any longer. IT DOES WORK! Case closed! 
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Guitarnut - Name: Scott Hansgen
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Sept 2011
- Age at diagnosis: 47
Re: Medical Cannabis Treatments?
I find it so difficult to understand why some folks are so ready to jump right into a treatment with "anything" with no proof that it actually works. On the other hand, if one wants to experiment on themselves with unconventional treatment, more power to ya. But to go into public conversations spewing the virtues of something as factual with nothing more than anecdotal evidence is mind boggling to me. I just don't get it, no matter how hard I try to understand it. Why state something as fact when it is not? Especially when it is something as serious as multiple myeloma.
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Guitarnut - Name: Scott Hansgen
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Sept 2011
- Age at diagnosis: 47
Re: Medical Cannabis Treatments?
I have just started taking the ROS oil, and I am also juicing every day to get CBD. I take 8 grams of curcumin a day and have been for the last 12 months. I eat a healthy diet.
I have not had any other treatment so far, just holding off. Last bloods everything had improved just slightly. I am currently waiting for next results, fingers crossed.
I have not had any other treatment so far, just holding off. Last bloods everything had improved just slightly. I am currently waiting for next results, fingers crossed.
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corrina69 - Name: corrina
- Who do you know with myeloma?: me
- When were you/they diagnosed?: october 2013
- Age at diagnosis: 51
Re: Medical Cannabis Treatments?
Kim and Chris wrote:
Hi there, Kim and Chris!
Can you please write how much RSO your husband took as a dose when he started using it? My dad has been told he's got just weeks and I don't want to lose time giving him wrong doses.
Thanks!
Despite being told on numerous occasions that he had weeks to live in March 2014, I started him on a high RSO dose and now he takes about a match head a day along with his skin cream and he is healthy, generally pain free and happy.
Hi there, Kim and Chris!
Can you please write how much RSO your husband took as a dose when he started using it? My dad has been told he's got just weeks and I don't want to lose time giving him wrong doses.
Thanks!
Re: Medical Cannabis Treatments?
Largest hospital in Israel and the Middle East to conduct research in the treatment for multiple myeloma with cannabinoids:
Source: "One World Cannabis Signed a Collaboration Agreement with Sheba Academic Medical Center," press release issued March 11, 2015 (link to full text at PR Newswire)
... the company will initiate a study to explore the effect of several combinations of cannabidiol (CBD) and tetrahydrocannabinol (THC) on multiple myeloma, starting with a basic science on multiple myeloma cells ...
Dr. Merav Leiba, Head of Multiple Myeloma outpatient clinic and Multiple Myeloma research lab at Sheba Academic Medical Center's hematology institute, will lead the research. Dr. Leiba, a specialist in Internal Medicine and Hematology, was a postdoctoral fellow at the Jerome Lipper Multiple Myeloma Center at Dana Farber Cancer Institute, Boston, Massachusetts (2006-2008). Dr. Leiba has participated in numerous clinical and investigational studies aimed at developing novel drugs for multiple myeloma ..."
Source: "One World Cannabis Signed a Collaboration Agreement with Sheba Academic Medical Center," press release issued March 11, 2015 (link to full text at PR Newswire)
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truthseeker
Re: Medical Cannabis Treatments?
You want the marijuana that contains CBD's, NOT the THC that gives you a buzz. Also, I have been using resveratrol for almost 9 years now and have had only the initial treatment with thalidomide and dex – nothing else. I also take 2000 IU's of vitamin D 3 times a day and consume 14 to 28 oz of black cherry juice a day, plus the normal dosage of other vitamins.
So far my tests for myeloma are coming back good – not remission, but good enough that I have not had any treatment since 2004-5.
I have not purchased any MJ but am looking into it. Seems there are 2 methods of consuming it – one by vaporizer (i.e. e-cigs), and liquid form. I don't put anything into my lungs except clean air if I can help it, so I guess I will be looking for the liquid form with CBD (it's supposed to be legal; no prescription needed)
NG
Matt wrote:
So far my tests for myeloma are coming back good – not remission, but good enough that I have not had any treatment since 2004-5.
I have not purchased any MJ but am looking into it. Seems there are 2 methods of consuming it – one by vaporizer (i.e. e-cigs), and liquid form. I don't put anything into my lungs except clean air if I can help it, so I guess I will be looking for the liquid form with CBD (it's supposed to be legal; no prescription needed)
NG
Matt wrote:
If the buzz from marijuana helps a person cope with having multiple myeloma or any other form of cancer, I don't have a problem with it. As John Lennon said, "Whatever gets you through the night." But I just wish people would be honest about it. I am not aware of any clinical trials that suggest that marijuana has anit-cancer effects. And that is what we go by.
Curcummin, resveratrol, etc are all being studied. Pre-clinical data suggests that these might be helpful for multiple myeloma. But I haven't heard anything about marijuana."
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Nipon Ginko - Name: Nipon Ginko
- Who do you know with myeloma?: ME
- When were you/they diagnosed?: 2004
- Age at diagnosis: 66
Re: Medical Cannabis Treatments?
A company to keep an eye on is Oxis International. Oxis does research and development of cannabinoid therapies for multiple myeloma
Xiang-Qun (Sean) Xie is on the Science Advisory board for Oxis Biotech (who holds exclusive development agreement for their cannabinoid based myeloma products with Oxis International)
Xiang-Qun (Sean) Xie has impressive credentials and has long been researching cannabinoid efficacy for multiple meyloma at the Drug Discovery Institute in Pittsburgh.
Anyway, nice to see some highly credentialed folks doing this research ... I'll be keeping an eye on Oxis and Xiang-Qun (Sean) Xie.
Excerpt from Oxis International press release:
Xiang-Qun (Sean) Xie is on the Science Advisory board for Oxis Biotech (who holds exclusive development agreement for their cannabinoid based myeloma products with Oxis International)
Xiang-Qun (Sean) Xie has impressive credentials and has long been researching cannabinoid efficacy for multiple meyloma at the Drug Discovery Institute in Pittsburgh.
Anyway, nice to see some highly credentialed folks doing this research ... I'll be keeping an eye on Oxis and Xiang-Qun (Sean) Xie.
Excerpt from Oxis International press release:
Sean Xie, MD, PhD, EMBA (one of the world's foremost cannabinoid research scientists) is a tenured Professor at the Department of Pharmaceutical Sciences/Drug Discovery Institute at University of Pittsburgh and Associate Dean for Research Innovation at the School of Pharmacy. He is Principal Investigator of an integrated research laboratory of CompuGroup, BioGroup and ChemGroup, and Founding Director of Computational Chemical Genomics Screening Center. Dr. Xie is also Director/PI of NIH funded National Center of Excellence for Computational Drug Abuse Research. Dr. Xie holds joint faculty positions at the Departments of Computational System Biology and Structural Biology, and Pittsburgh Cancer Institute MT/DD Program. Xie is a charter member of the NIH BPNS Study Section Review Panel, an oversea expert reviewer for the Chinese Natural Science Foundation, ad hoc reviewer for the Netherlands Organizations for Scientific Research Council for Chemical Sciences, MCMB Foundation for MRC UK, and the Wellcome Trust Fund, Sir Henry Wellcome Fellowship, London, UK. He serves as an invited guest editor for AAPS Journal, Editorial Board of American Journal of Molecular Biology, and Associate Editor of BMC Pharmacology and Toxicology. He was an invited international Assessment Panelist for Fudan University College of Pharmacy, a member of the Board of Directors of the Chinese Association of Professionals in Science and Technology, and a Chair of the CAPST Biomedical and Pharmaceutical Society. Dr. Xie also holds adjunct professor title in top institutes and colleges of pharmacy in China, including CAMS Tianjin Institute of Hematology Stem Cell Medical Center; Fudan, Shanghai Jiaotong, and Zhejiang Universities. In 2013, he was named an honorary professor of Chinese Academy of Medical Sciences & Peking Union Medical College. Dr. Xie is a recipient of the 2014 American Association of Pharmaceutical Scientists (AAPS) Outstanding Research Achievement Award.
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truthseeker
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