Hey Multibilly,
Thanks for the update. Glad to see that your main markers are at least holding steady. And it's good to see that your HGB is increasing a bit.
Keep on trucking!
Mike
Forums
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mikeb - Name: mikeb
- Who do you know with myeloma?: self
- When were you/they diagnosed?: 2009 (MGUS at that time)
- Age at diagnosis: 55
Re: Fenofibrate (Tricor) and multiple myeloma
Hi Multibilly,
Thanks for the update about your "mini clinical trial"
I'm glad that your M-spike stayed steady and that your FLC ratio also hasn't gone up.
Given your IgG level and the increase in both your FLC levels, without any increase in your FLC ratio, it seems like you may have had some sort of infection lately. Did you have any symptoms of one? If you did, I hope the symptoms (and the infection itself) have gone.
Thanks for the update about your "mini clinical trial"
I'm glad that your M-spike stayed steady and that your FLC ratio also hasn't gone up.
Given your IgG level and the increase in both your FLC levels, without any increase in your FLC ratio, it seems like you may have had some sort of infection lately. Did you have any symptoms of one? If you did, I hope the symptoms (and the infection itself) have gone.
Re: Fenofibrate (Tricor) and multiple myeloma
Hi Cheryl,
No infection that I know of and I feel fine. I therefore didn't try to read too much into those figures and will just wait to see what my next test results brings in 2-3 months.
No infection that I know of and I feel fine. I therefore didn't try to read too much into those figures and will just wait to see what my next test results brings in 2-3 months.
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Multibilly - Name: Multibilly
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Smoldering, Nov, 2012
Re: Fenofibrate (Tricor) and multiple myeloma
Hi Multibilly,
Interesting that you didn't notice any infection, although I can't say I'm totally surprised. I was just curious, since we often discuss here in the forum to what extent things other than myeloma can affect immunoglobulin and free light chain levels.
Thanks again for the update!
Interesting that you didn't notice any infection, although I can't say I'm totally surprised. I was just curious, since we often discuss here in the forum to what extent things other than myeloma can affect immunoglobulin and free light chain levels.
Thanks again for the update!
Re: Fenofibrate (Tricor) and multiple myeloma
Hi all,
I've been hovering quietly on the Beacon without logging in, but just received my latest blood results.
After 10 months on fenofibrate my M-spike remains stable (1g/dL) but my light chains continue to increase. My ratio is also the lowest it's been at 0,16. I've decided to add IP6 to my supplement regime and will report back in 3 month's time.
I'm trying again to post my lambda graph
I've been hovering quietly on the Beacon without logging in, but just received my latest blood results.
After 10 months on fenofibrate my M-spike remains stable (1g/dL) but my light chains continue to increase. My ratio is also the lowest it's been at 0,16. I've decided to add IP6 to my supplement regime and will report back in 3 month's time.
I'm trying again to post my lambda graph
- LambdaLC.jpg (90.31 KiB) Viewed 2380 times
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Spanish Mary - Name: Spanish Mary
- Who do you know with myeloma?: Self, MGUS
- When were you/they diagnosed?: May 2014
- Age at diagnosis: 59
Re: Fenofibrate (Tricor) and multiple myeloma
Below are my updated graphs with my latest test results as I continue my fenofibrate experiment.
My FLC ratio seems to have found its natural groove and has pretty much flatlined.
As always, I don't think one can draw any cause-and-effect conclusions from this experiment. But I am pretty content with the relative state of my numbers and I would be happy if they simply continued on in their current ranges. I started taking fenofibrate (Tricor) back in February 2014. I continue to take curcumin + bioperine, D3+K2, and a daily iron pill.
My FLC ratio seems to have found its natural groove and has pretty much flatlined.
As always, I don't think one can draw any cause-and-effect conclusions from this experiment. But I am pretty content with the relative state of my numbers and I would be happy if they simply continued on in their current ranges. I started taking fenofibrate (Tricor) back in February 2014. I continue to take curcumin + bioperine, D3+K2, and a daily iron pill.
- IgG.png (27.14 KiB) Viewed 2329 times
- MSpike.png (29.73 KiB) Viewed 2329 times
- LambdaFLC.png (29.3 KiB) Viewed 2329 times
- FLCRatio.png (27.39 KiB) Viewed 2329 times
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Multibilly - Name: Multibilly
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Smoldering, Nov, 2012
Re: Fenofibrate (Tricor) and multiple myeloma
This is very interesting. My husband was on Tricor, and during his diagnosis and his treatment, he let his script lapse and just quit taking it.
I may need to get him started on it again. He wasn't very good at taking it before. Unless I reminded him, it was hit or miss (more miss I think).
His HDL (good cholesterol ) was very low, and he was on this to raise it.
I may need to get him started on it again. He wasn't very good at taking it before. Unless I reminded him, it was hit or miss (more miss I think).
His HDL (good cholesterol ) was very low, and he was on this to raise it.
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dogmom - Who do you know with myeloma?: husband
- When were you/they diagnosed?: December 2015
- Age at diagnosis: 58
Re: Fenofibrate (Tricor) and multiple myeloma
Multibilly,
Do you remember what you and your doctors were thinking around the time of December 27, 2014 through July 15, 2015? Your M-spike and IgG were on a steady incline during that time period. Did you think you were progressing then or were you not concerned because your FLC ratio was fairly steady during that time period?
Do you remember what you and your doctors were thinking around the time of December 27, 2014 through July 15, 2015? Your M-spike and IgG were on a steady incline during that time period. Did you think you were progressing then or were you not concerned because your FLC ratio was fairly steady during that time period?
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FingersCrossed - Name: FingersCrossed
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Oct 2014 (Smoldering)
- Age at diagnosis: 44
Re: Fenofibrate (Tricor) and multiple myeloma
FC,
My local onc was more cool about that period than me and it taught me a lesson. He kept saying that he sees quite a bit of fluctuation in the above makers with his MGUS and smoldering multiple myeloma patients (especially his MGUS patients) and to give it more time before worrying too much.
As a result, I'm now more calm about these kinds of changes and also remind myself that I very likely will not be taking any action until such time that I start to develop any end-organ damage. But I admittedly will still get a little bit concerned if my numbers trend out of the one-standard-deviation range for more than 2-3 tests in a row (that is, move above the vertical bars on the above graphs for 4-6 months or more).
MikeB always correctly reminds us that you can never predict how things will go with multiple myeloma. But one thing I have found that is very comforting with smoldering multiple myeloma is to have a pretty good idea about what your plan of action will be should you progress (which doctor you will use and ultimately trust for treatment decisions, whether you would opt for a transplant or not, to be up on all the latest drug choices and tradeoffs so that you can ask good questions of your specialist before starting treatment, etc). Having those big questions settled ahead of time also takes a lot of angst out of the equation.
My local onc was more cool about that period than me and it taught me a lesson. He kept saying that he sees quite a bit of fluctuation in the above makers with his MGUS and smoldering multiple myeloma patients (especially his MGUS patients) and to give it more time before worrying too much.
As a result, I'm now more calm about these kinds of changes and also remind myself that I very likely will not be taking any action until such time that I start to develop any end-organ damage. But I admittedly will still get a little bit concerned if my numbers trend out of the one-standard-deviation range for more than 2-3 tests in a row (that is, move above the vertical bars on the above graphs for 4-6 months or more).
MikeB always correctly reminds us that you can never predict how things will go with multiple myeloma. But one thing I have found that is very comforting with smoldering multiple myeloma is to have a pretty good idea about what your plan of action will be should you progress (which doctor you will use and ultimately trust for treatment decisions, whether you would opt for a transplant or not, to be up on all the latest drug choices and tradeoffs so that you can ask good questions of your specialist before starting treatment, etc). Having those big questions settled ahead of time also takes a lot of angst out of the equation.
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Multibilly - Name: Multibilly
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Smoldering, Nov, 2012
Re: Fenofibrate (Tricor) and multiple myeloma
Thanks for posting these graphs, Multibilly. It is very generous of you to share your experiment with using Tricor and your personal data with everyone on the forum. It is useful to see the variation of values that can occur in MGUS and smoldering multiple myeloma. I have been struggling to get some perspective on my numbers, and this helps. I am glad that your numbers seem to be stable at this point. I have a few questions:
What program do you use to generate the beautiful graphs? I am using pencil and graph paper for mine at this point, but would like to be able to generate graphs on the computer.
What dose of curcumin+bioperine are you taking? What is D3+K2 and what dose are you taking?
Thanks, Ciro
What program do you use to generate the beautiful graphs? I am using pencil and graph paper for mine at this point, but would like to be able to generate graphs on the computer.
What dose of curcumin+bioperine are you taking? What is D3+K2 and what dose are you taking?
Thanks, Ciro
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ciro - Who do you know with myeloma?: me
- When were you/they diagnosed?: MGUS 2013, SMM Feb 2016
- Age at diagnosis: 62
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