Is there any cream or something to help with rash on the back of my arm from subcutaneous (subq, sub-q) Velcade injections?
Any ideas or medications?
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Re: Subcutaneous Velcade injections - rash, redness & welts
Barneasada wrote:
> Is there any cream or something to help with rash on the back of my arm
> from SubQ Velcade injection?
>
> Any ideas or medications?
I would be interested in this as well. I just had my sixth injection, and I can still see the 'marks' from the last five of 'em. In fact, I can time my days of feeling crappy by what that rash looks like. I'm not getting a whole lot of encouragement or help from my oncologist, who said, when I let him know that for the last week I was getting dizzy and lightheaded every time I stood up, "don't fall."
Gee.
Thanks, Doc.
So if anybody knows anything about that localized rash we get with the Velcade SubQ, I'd be interested, too.
> Is there any cream or something to help with rash on the back of my arm
> from SubQ Velcade injection?
>
> Any ideas or medications?
I would be interested in this as well. I just had my sixth injection, and I can still see the 'marks' from the last five of 'em. In fact, I can time my days of feeling crappy by what that rash looks like. I'm not getting a whole lot of encouragement or help from my oncologist, who said, when I let him know that for the last week I was getting dizzy and lightheaded every time I stood up, "don't fall."
Gee.
Thanks, Doc.
So if anybody knows anything about that localized rash we get with the Velcade SubQ, I'd be interested, too.
-
dianaiad - Who do you know with myeloma?: Me
- When were you/they diagnosed?: Officially...March 2013
- Age at diagnosis: 63
Re: Subcutaneous Velcade injections - rash, redness & welts
Hi there,
I had Velcade SubQ in my thighs for twice a month for almost a year and had an ugly rash each time. I also felt crappy for a few days after each injection.
I recently read the abstract below (from the IMW) where they suggest administration on the abdomen might be better.
/Åsa
Higher Incidence of Injection Site Reaction after Subcutaneous Bortezomib on the Thigh Compared with the Abdomen
T. KAMIMURA,1 T. MIYAMOTO,2 N. YOKOTA,3
Y. CHONG,1 Y. ITO,1 K. AKASHI2
1Department of Hematology, Harasanshin Hospital, Japan;
2Department of Medicine and Biosystemic Science, Graduate
School of Medical Science, Kyushu University, Japan;
3Department of Nursing, Harasanshin Hospital, Japan
Subcutaneous (sc) rather than intravenous administration of bortezomib (Bor) is becoming more common for treating multiple myeloma (multiple myeloma) because scBor results in lower incidence and severity of peripheral neuropathy and has equivalent effi cacy. Bor is an irritant cytotoxic agent when it leaks out; therefore, it is recommended that injections of scBor should be rotated among 8 diff erent sites on the abdomen and thigh. However, detailed information about injection site reactions (ISR) have not been suffi ciently documented.
We retrospectively analyzed the incidence and severity of ISR following scBor administration in 15 Japanese patients with multiple myeloma. Grade 1 ISR occurred following 40 of 158 (25.3%) sc-Bor injections in 10 patients, whereas grade 2 ISRs occurred following 7 injections (4.4%) in 5 patients. Five patients did not develop ISR. Of note, grade 2 ISR was documented in 6 of 63 (9.5%) thigh injections but only in 1 of 95 (1.1%) abdominal injections. These data show that grade 2 ISR were more common in the thigh compared with the abdomen possibly because the thigh contains lesser adipose tissue than the abdomen. Grade 2 ISRs resolved without any sequela within a median of 7 days. scBor administration on the abdomen instead of the thigh should be considered, especially for emaciated patients, because ISR rapidly resolves within the interval before the next injection even if it occurs.
I had Velcade SubQ in my thighs for twice a month for almost a year and had an ugly rash each time. I also felt crappy for a few days after each injection.
I recently read the abstract below (from the IMW) where they suggest administration on the abdomen might be better.
/Åsa
Higher Incidence of Injection Site Reaction after Subcutaneous Bortezomib on the Thigh Compared with the Abdomen
T. KAMIMURA,1 T. MIYAMOTO,2 N. YOKOTA,3
Y. CHONG,1 Y. ITO,1 K. AKASHI2
1Department of Hematology, Harasanshin Hospital, Japan;
2Department of Medicine and Biosystemic Science, Graduate
School of Medical Science, Kyushu University, Japan;
3Department of Nursing, Harasanshin Hospital, Japan
Subcutaneous (sc) rather than intravenous administration of bortezomib (Bor) is becoming more common for treating multiple myeloma (multiple myeloma) because scBor results in lower incidence and severity of peripheral neuropathy and has equivalent effi cacy. Bor is an irritant cytotoxic agent when it leaks out; therefore, it is recommended that injections of scBor should be rotated among 8 diff erent sites on the abdomen and thigh. However, detailed information about injection site reactions (ISR) have not been suffi ciently documented.
We retrospectively analyzed the incidence and severity of ISR following scBor administration in 15 Japanese patients with multiple myeloma. Grade 1 ISR occurred following 40 of 158 (25.3%) sc-Bor injections in 10 patients, whereas grade 2 ISRs occurred following 7 injections (4.4%) in 5 patients. Five patients did not develop ISR. Of note, grade 2 ISR was documented in 6 of 63 (9.5%) thigh injections but only in 1 of 95 (1.1%) abdominal injections. These data show that grade 2 ISR were more common in the thigh compared with the abdomen possibly because the thigh contains lesser adipose tissue than the abdomen. Grade 2 ISRs resolved without any sequela within a median of 7 days. scBor administration on the abdomen instead of the thigh should be considered, especially for emaciated patients, because ISR rapidly resolves within the interval before the next injection even if it occurs.
-
asaryden - Name: asaryden
- Who do you know with myeloma?: myself
- When were you/they diagnosed?: August 2010
- Age at diagnosis: 48
Re: Subcutaneous Velcade injections - rash, redness & welts
I hate to say this, but injection site reactions with subcutaneous Velcade seem to occur in many patients regardless of what part of the body is used.
Be sure that site of body is rotated with each injection.
Be sure that site of body is rotated with each injection.
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Dr. Jason Valent - Name: Jason Valent, M.D.
Beacon Medical Advisor
Re: Subcutaneous Velcade injections - rash, redness & welts
My Mother is taking dexamethasone, cyclophosphamide and Velcade injections once a week. She normally gets a big welt on the injection site which she gets on her stomach, but with her last injection a similar looking welt has come up on the opposite higher side to where her last injection was.
Is this normal, or some sort of allergic reaction to Velcade?
She usually gets a large case of the sneezes on the same night, but never experienced this with the last injection.
Is this normal, or some sort of allergic reaction to Velcade?
She usually gets a large case of the sneezes on the same night, but never experienced this with the last injection.
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Mish - Name: Mish
- Who do you know with myeloma?: Mother
- When were you/they diagnosed?: April 2014
- Age at diagnosis: 64
Re: Subcutaneous Velcade injections - rash, redness & welts
I have been getting Velcade injections in my belly all summer for a recurrence of myeloma. I get what looks like a 2 inch patch of sunburn at each injection site. I just coat it in hyrdocortisone, which takes away the itching. Usually it takes up to 5 days for the redness to go away, just like a sunburn.
The older sites are now a darker brown. I hope they will go away eventually but, if not, at least they are hidden in my clothes.
The older sites are now a darker brown. I hope they will go away eventually but, if not, at least they are hidden in my clothes.
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darnold - Name: Dana Arnold
- Who do you know with myeloma?: self
- When were you/they diagnosed?: May 2009
- Age at diagnosis: 52
Re: Subcutaneous Velcade injections - rash, redness & welts
I always get a red rash after self injection of Velcade. Doesn't itch much and disappears after a week or so.
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coop223 - Name: derek cooper
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: November 2011
- Age at diagnosis: 57
Re: Subcutaneous Velcade injections - rash, redness & welts
My experience was exactly as darnold described. I just put Vaseline Intensive Care lotion on the spot. Not sure if that helped or not. And the "sunburn reaction" happened sometimes when I got the injection, but not always.
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mikeb - Name: mikeb
- Who do you know with myeloma?: self
- When were you/they diagnosed?: 2009 (MGUS at that time)
- Age at diagnosis: 55
Re: Subcutaneous Velcade injections - rash, redness & welts
Hi Mike. Did your "sunburn" patches fade eventually? Mine turned brown, like a sunburn tans, but none of them have faded. I got the first one back in June, through last week. Unlike a suntan, they are not a trophy I'd like to keep.
Dana A
Dana A
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darnold - Name: Dana Arnold
- Who do you know with myeloma?: self
- When were you/they diagnosed?: May 2009
- Age at diagnosis: 52
Re: Subcutaneous Velcade injections - rash, redness & welts
Hi Dana, the sunburn-like patches did fade. Now all I see on my legs are freckles. As for Velcade skin changes on my stomach, I don't think any changes are still there either. But I don't spend any time looking at my stomach because it depresses me since it's too large. But that's another issue. 
Mike
Mike
-
mikeb - Name: mikeb
- Who do you know with myeloma?: self
- When were you/they diagnosed?: 2009 (MGUS at that time)
- Age at diagnosis: 55
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