Forums
Re: M Spike
Hi,
The m spike is usually listed under the protein electrophoresis, serum. It will say a restricted band consistent with a monoclonal protein is present. Recommend serum immunofixation for confirmation and identification.
Then right under that you will see a list that reads albumin,alpha-1-globulin, alpha-2-globulin , beta globulin, gamma globulin, and finally the M-Spike.
Hope this helps.
The m spike is usually listed under the protein electrophoresis, serum. It will say a restricted band consistent with a monoclonal protein is present. Recommend serum immunofixation for confirmation and identification.
Then right under that you will see a list that reads albumin,alpha-1-globulin, alpha-2-globulin , beta globulin, gamma globulin, and finally the M-Spike.
Hope this helps.
-
Joe C
Re: M Spike
Thank you for getting back with me, but my husband's test never mentions the M Spike. So I don't know.
Re: M Spike
My 'M' spike is listed under 'monoclonal protein(s). There is no 'normal' for monoclonal proteins, although a low level can indicate a stable disease. I did write a column about blood tests, from a personal point of view, called 'Watching the Detectives'.
URL to article: https://myelomabeacon.org/headline/2013/03/14/northern-lights-watching-the-detectives/
I think that your husbands M protein is listed under 'Quant monoclonal protein' on your other post. It is in the section on immunofixation. The capital letter 'H' indicates 'high'.
Hope that helps!
URL to article: https://myelomabeacon.org/headline/2013/03/14/northern-lights-watching-the-detectives/
I think that your husbands M protein is listed under 'Quant monoclonal protein' on your other post. It is in the section on immunofixation. The capital letter 'H' indicates 'high'.
Hope that helps!
-
Nancy Shamanna - Name: Nancy Shamanna
- Who do you know with myeloma?: Self and others too
- When were you/they diagnosed?: July 2009
Re: M Spike
Thank you Nancy! So I am gathering that is our m spike. It just gets very confusing when everyone talks about their m spike and I don't have that to base it on. I know his numbers are high that's why I am trying to figure out if he is relapsing, very overwhelming trying to figure this out. Thank you again for your help
Re: M Spike
On my list of tests it is noted as SPEP. There is an explanation of the results noting a number such as 1.2 g/dl in the gamma region. It also notes whether it is polyclonal or monoclonal and whether there is paresis or not. Then it may recommend some follow-up tests to do.
Nancy in Phila
Nancy in Phila
-
NStewart - Name: Nancy Stewart
- Who do you know with myeloma?: self
- When were you/they diagnosed?: 3/08
- Age at diagnosis: 60
Re: M Spike
Hi Again Cgrundy, I am not a doctor, but after more than four years of reading my lab tests I am familiar with them. My oncologist always goes thru the lab tests with me and we talk about any problems then. Wishing you and your husband all the best!
-
Nancy Shamanna - Name: Nancy Shamanna
- Who do you know with myeloma?: Self and others too
- When were you/they diagnosed?: July 2009
Re: M Spike
Hi Cgrundy, remember that about 20% of myeloma patients don't have a traditional M-spike as found in the SPEP, not an insignificant number. We are light chain only. Our SPEP's are usually completely normal. It usually takes doctors longer to discover our disease. Our disease is primarily tracked by the free light chain assay and serum and urine immunifixation. It is possible your husband is light chain only. Ask the doctor. Good luck.
-
terryl1 - Name: Terry
- Who do you know with myeloma?: self
- When were you/they diagnosed?: August 10, 2011
- Age at diagnosis: 49
Re: M Spike
One other thought...my husband's hematologist was only doing the immunofixation and tracking his myeloma only by the IgG readings. It was only when we requested that the M spike be tested that he ordered the SPEP test... so maybe if you aren't seeing it on the lab results it isn't being checked.
-
Babs
12 posts
• Page 1 of 2 • 1, 2