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General questions and discussion about multiple myeloma (i.e., symptoms, lab results, news, etc.) If unsure where to post, use this discussion area.

Re: What does a value of 1 mean for M protein?

by TaraS on Fri Jul 19, 2013 12:33 am

I was told Monday that my M-Spike was 0.3, all other bloodwork was normal. My symptoms are fatigue, numbness in one toe on my left foot, and my pupils dilate unevenly. I have psoriasis and I'm 36. I see a hematologist tomorrow.

I am very nervous. I just had my 4th child, he's 4 months. The last thing I want to worry about is cancer.

TaraS

Re: What does a value of 1 mean for M protein?

by BobRobert on Wed Sep 18, 2013 6:15 pm

I am trying to make some sense of my recent blood work, with previous doctors ( I have been trying to find a doctor I am comfortable with).

The M protein was labeled as such ... seems that in a recent 24-hour urine test, it shows 11% M-spike. I was used to my serum M protein being 1.0 and don't understand 11%.

Also, in 3 months my free kappa/lambda ratio went from 13 to 16. It should be below 1. When should I be worried?

Recent (difference center) tests showed elevated kappa Light chains, value was approximately 130. Can't find any related value from this new blood test.

I have a consultation with the doctor tomorrow, I am not happy with this supposed great new cancer center.

BobRobert

Re: What does a value of 1 mean for M protein?

by ethomas on Thu Nov 13, 2014 11:45 am

In my blood test report, what do I look for? How is M protein labeled as?

ethomas
Name: Emmanouel Thomas AKA Amo
Who do you know with myeloma?: Yes
When were you/they diagnosed?: August 14, 2014
Age at diagnosis: 65

Re: What does a value of 1 mean for M protein?

by novalachance on Wed Mar 11, 2015 12:54 pm

I was looking for some info regarding some upcoming tests, and now this worries me. I had an M-protein value of 8.7.

novalachance

Re: What does a value of 1 mean for M protein?

by novalachance on Wed Mar 11, 2015 1:46 pm

Obviously this was from previous values of 3 - 4, which were being monitored. However, tests have revealed no answers over time.

novalachance

Re: What does a value of 1 mean for M protein?

by Jonah on Wed Mar 11, 2015 1:49 pm

What are the units for your M-protein level? Are they g/L or g/dL?

In all the postings above, the M-spike of 1 that everyone is referring to is an M-spike of 1 g/dL. Units of g/dL are what are most commonly used in the U.S. for M-spike measurement.

Outside the U.S., however, M-spikes (M-protein levels, monoclonal protein levels, paraprotein levels -- they all mean the same thing) are usually measured in g/L. A U.S. M-spike of 1 g/dL is equivalent to an M-spike of 10 g/L. You multiply U.S. M-spikes by 10 to get the equivalent in g/L, and divide g/L results by 10 to get g/dL.

Jonah

Re: What does a value of 1 mean for M protein?

by niswonger on Thu Aug 06, 2015 3:17 pm

My M protein seems frightening. It has crept up in three years from 3 to 12.2. How afraid should I be?

niswonger

Re: What does a value of 1 mean for M protein?

by JPC on Thu Aug 06, 2015 8:55 pm

Hello, Nis:

As Jonah had mentioned in the previous post on this thread, it depend on the units (where you live, and where is the lab that you use to get your blood tests).

If you are at 12.2 g/L, which equals 1.2 g/dL (g/dL are the typical US units), you are probably OK for now, but you need to follow up (say every 3 months).

If you are at 12.2 g/dL (which equals 122 g/L), that is very, very high, and you need to get it looked at sooner rather than later.

In either case, try not to get scared. If you only have an M-spike and no (or very few) symp­toms, you are probably in decent shape as long as the condition is being addressed.

Good luck

JPC
Name: JPC

Re: What does a value of 1 mean for M protein?

by mikele on Tue Oct 06, 2015 12:36 am

Diane,

I am 54 and was diagnosed in May with 2 spikes. Get a biopsy. My good versus bad cell count is 30/70. I am going in January and February for heavy dose chemo and a bone marrow transplant.

I didn't have any symptoms and still don't other than now aching bones. I've always been very healthy and active and work 7 days a week, so no slug. It's nothing to look forward to, but get checked. Mine is pill therapy right now and I feel good. I'm far from anxious for my curtain call early next year, but it'll be ok. I'm here if I can help you. It's a scary thing. You'll be ok.

mikele

Re: What does a value of 1 mean for M protein?

by Abbie on Sat Jan 23, 2016 11:14 am

My husband was diagnosed with multiple myeloma in January of 2014 after losing the ability to walk second to a tumor on T-8, which caused three compression fractures. He had 6 rounds of chemo in 2014 and a stem cell transplant in August of 2014. Since then his protein levels have been trace or zero and he is walking again and has been doing great.

This past week his oncologist said his protein went to 0.6. She is starting him on dexa­metha­sone 20 mg once a week. We are concerned that this may be a trend of increasing protein.

Is this a usual course 2 years post stem cell transplant? Do we have cause to be concerned about a trend or can this be controlled and go back to trace?

He is also taking Revlimid every day at 5 mg.

Thank you.

Abbie

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