[jlasiter]

Liver damage from curcumin with bioperine?

by jlasiter on Mon Mar 05, 2018 2:53 pm

My doctor wants me to stop curcumin with bioperine due to potential liver damage. Does anyone know about this?

[MikeJr]

Re: Liver damage from curcumin with bioperine?

by MikeJr on Mon Mar 05, 2018 6:13 pm

Question: What else are you taking?

Also, are your AST/ALT readings currently abnormal?

[JimNY]

Re: Liver damage from curcumin with bioperine?

by JimNY on Tue Mar 06, 2018 12:05 pm

See the article mentioned in this forum thread,

"The dark side of curcumin?" (started Feb 3, 2013)

Note this text near the end of the article:

"It is unfortunate that curcumin is regarded in the scientific literature as efficient and safe when its efficiency and safety have not yet been proven. The fact that curcumin is a common dietary con­stituent is not enough to prove its safety, as other com­mon dietary constituents have shown toxicity when used as dietary supplements. The fact that no major toxicity has been found in short-term studies in humans is not a proof of curcumin safety either. For a drug to be safe, it must also be devoid of long-term toxicity, and the most com­plete long-term toxicity study conducted to date raises concern about curcumin safety."

The article also mentions that curcumin is metabolized in the intestine and the liver. Thus, the liver would be one of the organs you would expect to be negatively affected by "high" doses of curcumin.

[jlasiter]

Re: Liver damage from curcumin with bioperine?

by jlasiter on Tue Mar 20, 2018 10:21 am

Latest Result from Yesterday:

AST=36 U/L (ref range <37 U/L)

ALT=65 U/l (High). (ref Range <55 U/L)

Had a few drinks night before, not sure if that's the reason for the elevation.