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General questions and discussion about multiple myeloma (i.e., symptoms, lab results, news, etc.) If unsure where to post, use this discussion area.

bone scan and multiple myeloma

by shehadi88 on Mon Feb 06, 2012 9:18 pm

My father is currently being worked up for multiple myeloma. He had a bone scan today that showed arthritic bones and it said scan not woresome for bone mets. This is good sign that my dad doesnt Have multiple myeloma right? But isn't there a difference between a general bone scan with dye and Thistles spec scan? I know we are still waiting for the UPEP and SPEP. I was just wondering could a bone scan not nessessarily show multiple myeloma? is there still a chance he could have it?

Chrissy

shehadi88

Re: bone scan and multiple myeloma

by shehadi88 on Mon Feb 06, 2012 9:19 pm

Thistle is not supposed to be in there! Spec bone scan is what I meant

shehadi88

Re: bone scan and multiple myeloma

by Art on Mon Feb 06, 2012 11:29 pm

Hi shehadl88
The Bone scan may not show anything. The SPEP and UPEP should be a good start. He should also have a Bone Marrow Biopsy. If he has a plasma cell percentage of more than 10% in his Bone Marrow and Monoclonal proteins in his Serum and/or His Urine but no bone involvment then he may have Smoldering Myeloma as long as his Kidney function is good(creatinine), his Hemoglobin is not low and his cacium level in his Blood is normal. These are called the CRAB features. Try this link for more info. https://myelomabeacon.org/search/crab
Hope this helps and good luck
Art

Art
Name: Art
Who do you know with myeloma?: Self
When were you/they diagnosed?: 12/2011
Age at diagnosis: 40

Re: bone scan and multiple myeloma

by Billy1 on Tue Feb 07, 2012 4:14 pm

Although the full bone X-Ray survey has been the gold standard in the past for detection of bone lesion's it is no longer considered adequate by most major cancer centers which usually specify MRI or Pet scan as a backup to this test in part because the x-rays cannot detect small lesion's to a specific degree.
In fact the new Dore-Salmon PLUS staging system (2006) now makes imaging techniques as part of the criteria for staging of multiple myeloma.

Billy1

Billy1

MGUS and Multiple Myeloma

by bartmelly on Wed Feb 08, 2012 10:06 am

I had Dr. Landgren from National Cancer Institute on my radio show talking about MGUS and Multiple Myeloma. You can access the archived interview at http://www.voiceamerica.com/episode/59330/mgus-and-survival-of-head-and-neck-cancer. ( I also had a survivor of head and neck cancer Michele Howe Clarke tell her story). You can access any of my shows at http://www.voiceamerica.com/show/1929/the-dr-melanie-show. I have been diagnosed with MGUS myself.

bartmelly

Re: bone scan and multiple myeloma

by Art on Wed Feb 08, 2012 1:12 pm

Dr Landgren is a brilliant multiple myeloma Doctor. I just went to see him last week. Kind,caring and Compassionate too.

Art
Name: Art
Who do you know with myeloma?: Self
When were you/they diagnosed?: 12/2011
Age at diagnosis: 40

Re: bone scan and multiple myeloma

by suzierose on Thu Feb 09, 2012 1:23 am

ART

Cant hot link to your name for mesages. Not ignoring.

suzierose
Name: suzierose
When were you/they diagnosed?: 2 sept 2011

Re: bone scan and multiple myeloma

by ninja performance on Fri Feb 10, 2012 4:26 pm

While they were trying to figure out what was wrong with me after being admitted to the hospital with a 6.3 HGB, they did a full Xray body scan and even though I had bone pain in ribs and spine, nothing showed up on the xray.

Then the tests came back 8.9 mspike ad 80% marrow.

Knowing I had pain even though no lesions showed on the xrays AND I had Hypercalcemia, I knew there was some bone involvement. After my 5 cycles of chemo, I finally had a PET scan done. It showed "multiple levels of osteolytic changes in ribs and spine common in treated multiple myeloma"

So it did not show up on xrays but did on a PET.

-Chris

ninja performance
Name: Chris Hill
Who do you know with myeloma?: Self
When were you/they diagnosed?: 08/04/2011
Age at diagnosis: 43

Re: bone scan and multiple myeloma

by Dr. Edward Libby on Sun Feb 12, 2012 2:30 pm

Hello from cloudy and gray Seattle!
Sometimes the nomenclature of medicine is confusing so one can never be sure what is meant by "bone scan".

In general medical use, the term "bone scan" refers to the use of injectable radiolabeled technicium ( technetium-99 a radioactive tracer). Technetium bone scans are not valuable in the workup of multiple myeloma because they are designed to be sensitive to the presence of "blastic" bone lesions (seen in breast cancer for instance) but not "lytic" lesions which are the classic bone lesions of myeloma. Unfortunately technetium bone scans are often mistakenly ordered in the workup of myeloma.

Sometimes a bone density test is referred to as a "bone scan" but this test is not designed to screen for myeloma either.

The skeletal survey ([XRAYS of skull, entire spine, pelvis, ribs, both humeri and femora (proximal long bones)] is the classic and still accepted, first line radiographic screening test for multiple myeloma.

A bone marrow MRI is also often used to screen for myeloma and is more sensitive to subtle bony myeloma lesions than the skeletal survey.

Dr. Edward Libby
Name: Edward Libby, M.D.
Beacon Medical Advisor

Re: bone scan and multiple myeloma

by ninja performance on Sun Feb 12, 2012 8:30 pm

My full body scan at DX which showed nothing was nothing more than an every day Xray. Nothing was injected or swallowed.

The post chemo therapy PET last week however showed multiple level osteolytic changes in the ribs and vertebral bodies with no FDG avidity.

-Chris

ninja performance
Name: Chris Hill
Who do you know with myeloma?: Self
When were you/they diagnosed?: 08/04/2011
Age at diagnosis: 43

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