[suzierose]

Re: bone scan and multiple myeloma

by suzierose on Sun Feb 12, 2012 10:13 pm

Hi Ninja!

From what I understand PET scans are prognostic for PFS and OS in myeloma.

"Among PET/CT-positive patients, 44% showed ≥ 3 FLs, 46% had SUV values > 4.2 and in 6% EMD could be detected. These 3 variables adversely affected 4-year estimates of PFS and OS. In particular, both EMD and severe FDG uptake were significantly associated with shorter PFS and OS....snip.....both severe PET/CT involvement at diagnosis (SUV > 4.2 and/or EMD) and persistence of FDG uptake after ASCT were independent predictors of worst PFS (SUV > 4.2= HR: 2.0, 95%CI: 1.13-3.72; EMD= HR: 15.0, 4.0-55.8; FDG uptake after ASCT= HR: 2.12, 1.19-3.77) and OS (EMD= HR: 6.99, 2.28-21.46; FDG uptake after ASCT= HR: 3.57, 1.03-12.39)."

http://myeloma.org/cgi-bin/mt/ArticlePage.action?tabId=0&menuId=0&articleId=3629&aTab=-1&tBack=&tDisplayBack=true


You would want to ask what your SUV (standardized uptake values) were.

http://www.ajronline.org/content/184/4/1199.full
http://ctscan.imagingeconomics.com/post/2011/10/31/PETCT-as-Prognosis-Tool-in-Multiple-Myeloma-Patients.aspx




and from the Beacon:
https://myelomabeacon.org/news/2011/09/21/results-of-petct-scans-may-predict-survival-in-multiple-myeloma-patients/

[ninja performance]

Re: bone scan and multiple myeloma

by ninja performance on Sun Feb 12, 2012 11:42 pm

Thanks Susie,

The only SUVs listed in my PET scan papers is:
Average Liver SUV measures 1.6
and
Very mild FDG uptake fusing to a partially sclerotic density in the right anterior fifth rib at the costochondral junction (where rib meets cartilage) with an SUV max of 1.6 (TP 520.8), may represent resolving trauma.

Not sure if they got the sides mixed up, cause at that spot, but on the left, I still hurt pretty bad most of the time.

Most everything else states no abnormal foci of increased FDG uptake to suggest active Myeloma disease.

Chris