Articles tagged with: Zolinza
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Dr. Kenneth Anderson, a world-renowned myeloma specialist, physician and researcher at Dana-Farber Cancer Institute, and Kraft Family Professor at Harvard Medical School, spoke with The Myeloma Beacon about his approach to treating multiple myeloma patients.
This article is the second part of a two-part series based on The Myeloma Beacon’s interview with Dr. Anderson. It will cover Dr. Anderson’s thoughts on where myeloma treatment is headed in the coming years. For more information on Dr. Anderson’s current approach to treating multiple myeloma, please see part one of this series.
Emerging Therapies …
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The results of a number of clinical trials for the treatment of multiple myeloma with Zolinza were presented at the American Society of Hematology (ASH) 2010 annual meeting. The trials, ranging from Phase 1 to Phase 3, studied Zolinza in combination with a variety of approved myeloma drugs for the treatment of both early and advanced stages of the disease.
Zolinza (vorinostat) is manufactured by Merck Pharmaceuticals. It is currently approved for a certain type of lymphoma and is being investigated as a treatment for multiple myeloma (see related Beacon …
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The American Society of Hematology meeting swung into full gear yesterday. The day was full of invited talks and a poster session.
The morning kicked off with an education session in which attendees could learn about several myeloma-related topics.
The first presentation was by Dr. Ola Landgren from the National Cancer Institute and National Institutes of Health in Bethesda, Maryland. Dr. Landgren spoke about monoclonal gammopathy of undetermined significance (MGUS) and smoldering myeloma, precursor diseases of multiple myeloma.
A study published by Dr. Landgren last year showed that all multiple myeloma patients have …
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Friday, June 4, was the first day of this year's American Society of Clinical Oncology (ASCO) annual meeting in Chicago. Most of the big multiple myeloma news of the day came out of a poster session in the afternoon.
At "poster sessions," researchers present a poster-sized summary of their research in a small, 2 meter by 1 meter cubicle. Researchers and physicians mill about, taking pictures of the posters with their cell phone cameras or taking notes. Sometimes one or more of the contributing researchers are present to answer questions. More often than …
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The results of a recent study suggest that Zolinza (vorinostat), in combination with Velcade (bortezomib), may be effective in patients with relapsed or refractory myeloma after prior treatment with Velcade. The study was published in the journal Clinical Lymphoma, Myeloma & Leukemia.
Velcade has become a standard first-line treatment option for multiple myeloma, but more and more patients are developing resistance to or relapsing after it. Zolinza is a new cancer drug that is already approved for a certain form of lymphoma. Preclinical trials suggest that it enhances …
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The 2009 American Society of Hematology (ASH) Meeting showcased several presentations on Zolinza (vorinostat), a histone deacetylase inhibitor developed by Merck Pharmaceuticals that is currently investigated for the treatment of multiple myeloma.
Zolinza alters the way a cancer cell’s DNA creates proteins, which is important in cancer treatment because such a drug can slow down cell proliferation, minimize mutations in DNA and control cell death.
Zolinza With Revlimid And Dexamethasone
Preliminary data from an ongoing Phase 1 study suggest that the combination treatment of Zolinza, Revlimid (lenalidomide) and …
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Brand Name: | Zolinza |
Generic Name: | vorinostat |
Code Name: | MK0683 |
Company: | Merck Pharmaceuticals |
FDA Clinical Phase: | 1, 2, & 3 |
Description:
Zolinza (news articles), which is an approved drug for cutaneous T-cell lymphoma, is also being studied in combination with Velcade (bortezomib) for treatment of multiple myeloma. Zolinza is a histone deacetylase (HDAC) inhibitor, which modifies the …