The findings of a recent retrospective study may alleviate some of the concerns patients and physicians have had about Revlimid and the risk of secondary cancers.
The study found that the risk of developing a secondary cancer as a result of treatment with Revlimid occurred mainly when a patient had been treated with oral melphalan at the same time as Revlimid.
Revlimid (lenalidomide) did not appear to be associated with an increased risk of secondary cancers when administered together with
Read the full story »
The year 2013 is likely to be remembered as a very good year when it comes to research related to multiple myeloma.
Previous years have witnessed research shedding new light on existing myeloma therapies, as well as additional research about potential new therapies.
But, in the past, most of the important new therapies that were being researched were from existing classes of therapy, making them less likely to offer dramatic improvements in the treatment of the disease.
In 2013, not …
Read the full story »
Each year, The Myeloma Beacon publishes many news articles summarizing the latest research findings about multiple myeloma. As in recent years, 2013 was a year filled with important multiple myeloma-related news.
During 2013, a new drug, Pomalyst, was approved for the treatment of multiple myeloma; researchers presented new findings about other potential new treatments; experts learned more about the factors that influence a patient’s prognosis and reported improvements in survival over the past decade; the role of stem cell transplantation and …
Read the full story »
At the 2013 annual meeting of the American Society of Hematology (ASH), which took place in December, there were many oral and poster presentations about Pomalyst, the newest drug approved in the United States and Europe for the treatment of multiple myeloma.
Many of the presentations were about studies of Pomalyst (pomalidomide, Imnovid) and dexamethasone (Decadron) in combination with a third drug, such as Velcade (bortezomib), Kyprolis (carfilzomib), clarithromycin (Biaxin), cyclophosphamide (Cytoxan), …
Read the full story »
More than twenty presentations about studies involving Pomalyst were presented at this year’s meeting of the American Society of Hematology (ASH), which took place last month.
Several of these presentations were about the Phase 3 clinical trial that found Pomalyst (pomalidomide, Imnovid) plus low-dose dexamethasone (Decadron) significantly improved overall survival of relapsed and refractory myeloma patients compared to high-dose dexamethasone alone (see related Beacon news). This is the study that led to the approval of pomalidomide …
Read the full story »
Initial results from a Phase 1 clinical trial show promise for SAR650984 as a therapeutic option for heavily pretreated multiple myeloma patients.
SAR650984 is one of several potential new anti-myeloma agents for which clinical results were first presented at the American Society of Hematology (ASH) meeting last week.
The results were presented by Dr. Joseph Mikhael from the Mayo Clinic in Scottsdale, Arizona, who told The Beacon, “This drug was hands down the most promising new agent at ASH for …
Read the full story »
Monday was the third day of this year’s meeting of the American Society of Hematology (ASH). The day was filled with oral presentation sessions from early in the morning until into the evening.
In the afternoon and early evening, there were six oral presentation sessions devoted solely to multiple myeloma and a number of other myeloma-related presentations scattered about the afternoon. The topics of these presentations ranged from the biology of myeloma to treatment options for newly diagnosed, relapsed and …
Read the full story »