Articles tagged with: Revlimid

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[ by and | Dec 11, 2013 6:20 pm | Comments Off ]
ASH 2013 Multiple Myeloma Update - Day Three: Afternoon Oral Sessions

Monday was the third day of this year’s meeting of the American Society of Hematology (ASH).  The day was filled with oral presentation sessions from early in the morning until into the evening.

In the afternoon and early evening, there were six oral presentation sessions devoted solely to multiple myeloma and a number of other myeloma-related presentations scattered about the afternoon.  The topics of these presentations ranged from the biology of myeloma to treat­ment options for newly diag­nosed, re­lapsed and refractory, and older patients.

This ASH update highlights most of the oral …

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[ by | Dec 9, 2013 1:13 pm | 2 Comments ]
ASH 2013 Multiple Myeloma Update - Day Two

Yesterday was the second day of the American Society of Hematology’s (ASH) annual meeting, which is being held in New Orleans.

As on Saturday, myeloma-related presentations were once again made during several sessions throughout the day.

Experts who missed the education session on Saturday had the opportunity to attend the session again early Sunday morning.

One myeloma study was presented during the plenary session in the early afternoon. The six presentations in this session covered all blood cancers and are considered particularly important studies.

The myeloma study included in this session was …

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[ by | Dec 8, 2013 5:16 pm | 4 Comments ]
ASH 2013 Multiple Myeloma Update - Day One

This year’s meeting of the American Society of Hematology (ASH) began yesterday morning in New Orleans.

Myeloma-related presentations were made during several sessions yesterday.

Two sessions were designed to better educate physicians about multiple myeloma and how to treat the disease.

The key myeloma-related research presented yesterday was made public during a poster session in the evening about the biology of myeloma as well as pre­clin­i­cal and clin­i­cal studies testing new and existing treat­ments for myeloma.

During the session, research results were made avail­able for review by meeting attendees in the form …

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[ by | Dec 2, 2013 5:12 pm | 2 Comments ]
ASH 2013 Preview: Revlimid Maintenance Therapy For Multiple Myeloma

Results of several studies investigating Revlimid main­te­nance ther­a­py for mul­ti­ple myeloma will be presented at this year’s American Society of Hema­tol­ogy (ASH) annual meeting, which starts later this week.

Today’s article previews the results of the key Revlimid main­te­nance studies that will be presented at the meeting, drawing on findings pub­lished in the meeting abstracts.  Some of the study results, it should be noted, will be updated during the presentations at ASH this week and early next week.

The results to be presented at ASH are unlikely to settle the ongoing debate …

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[ by and | Nov 26, 2013 12:04 pm | 4 Comments ]
Extended Post-Transplant Treatment With Revlimid, Velcade, And Dexamethasone Yields High Survival Rates In High-Risk Myeloma

A new retrospective study by Emory University researchers may stir de­bate about the best way to treat high-risk myeloma patients.

The researchers investigated treating high-risk myeloma patients for up to three years with a combination of Revlimid, Velcade, and dex­a­meth­a­sone.

The extended three-drug ther­a­py, which the authors describe as a com­bined con­sol­i­da­tion/​main­te­nance regimen, was initiated after the pa­tients had re­ceived a stem cell transplant.  The patients' transplants were car­ried out soon after completion of the first (induction) treat­ment reg­i­men fol­low­ing diagnosis.

Some, but not all, of the patients also received the Revlimid-Velcade-dexamethasone …

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[ by | Nov 7, 2013 9:02 am | Comments Off ]

Study is one of more than 160 abstracts eval­u­ating 10 Celgene com­­pounds across a range of blood cancers

Initial Phase III Results Of The FIRST Trial (MM-020/​IFM 07 01) In Newly Diagnosed Multiple Myeloma (NDMM) Patients (PTS) Ineligible For Stem Cell Trans­plan­tation (SCT) Accepted For Plenary Presentation At ASH Annual Meeting Boudry, Switzerland (Press Release) - Celgene Inter­na­tional Sàrl, a wholly-owned sub­sid­i­ary of Celgene Corpo­ra­tion (NASDAQ:CELG) today announced that data from FIRST® (Frontline Investigation of Lena­lido­mide + Dexa­meth­a­sone Versus Standard Thalido­mide), its phase III study (MM-020/IFM 07-01) of REV­LI­MID® (lena­lido­mide) in com­bi­na­tion with dex­a­meth­a­sone in patients newly diag­nosed with multiple myeloma (NDMM) in­eli­gible for stem cell trans­plant will be presented on Sunday, Dec. 8 during the plenary session of the 55thAmerican Society of Hematology annual meeting in New Orleans, La.

Abstracts for the meeting were released today on the society’s …

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[ by and | Oct 4, 2013 7:28 pm | 8 Comments ]
Extended Use Of Revlimid Plus Dexamethasone Delays Progression Of Relapsed / Refractory Myeloma

Results from a recent retrospective study conducted in France indicate that long-term treat­ment with Revlimid plus dex­a­meth­a­sone is effective in delaying dis­ease progression in relapsed multiple myeloma patients.

Among patients treated with Revlimid (lenalidomide) plus dex­a­meth­a­sone (Dec­a­dron) for at least two years, almost all (96 percent) responded to treat­ment, with 74 percent achieving at least a very good partial re­sponse.

Patients who received treat­ment for at least three years were significantly more likely to have not yet progressed 37 months after beginning treat­ment (91 percent), compared to patients who …

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