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Discussion about multiple myeloma treatments, stem cell transplants, clinical trials, alternative medicines, supplements, and their benefits and side effects.

What nausea medications work?

by Terrij on Tue Aug 18, 2015 9:19 pm

What nausea medications work?

Compazine (pro­chlor­per­a­zine) does not work for my daughter, but Zofran (on­danse­tron) has been her best friend until now. She just went through back-to-back DCEP treatments. Zofran worked through the first one, but she is so nauseous from the second round.

Any recommendations?

Terrij

Re: What nausea medications work?

by rumnting on Fri Aug 21, 2015 9:43 am

In a comment on his most recent column, Pat Killingsworth named some specific drugs that have helped him through tough times with treatment-induced nausea. He wrote:

Yes, besides standards Zofran and Compazine (Ativan worked best for me in my first transplant), granisetron helped. But a little used drug (used to help bipolar patients, so use is off label), olanzapine, worked like a miracle. It even helped chasing nausea; after it had already started. Just a little pill dissolved under the tongue.

rumnting
Who do you know with myeloma?: husband
When were you/they diagnosed?: 4/9/11
Age at diagnosis: 54

Re: What nausea medications work?

by Mike F on Fri Aug 21, 2015 10:27 am

Compazine didn't really work for me, either. Ativan was very effective, though.

Mike F
Name: Mike F
Who do you know with myeloma?: Me
When were you/they diagnosed?: May 18, 2012
Age at diagnosis: 53

Re: What nausea medications work?

by antelope1225 on Fri Aug 21, 2015 3:14 pm

Hi Terryj.

i Hope your daughter is doing better today. Some things that helped me were:

1. Small amounts of food
2. Yogurt or a smoothie
3. Ginger tea
4. Ginger ale (especially if it has real ginger in it)
5. A little coriander in water is good for digestive system
6. if I have heartburn, I put about 1 tbsp apple cider in about 1/2 cup water and drink it slowly.

I will warn you that I had a stomach ache long enough after ASCT that my doctor ordered an endoscopy. That doctor put me on omeprazole (Prilosec) – forever. After taking it for a year and still having stomach aches, I slowly weaned myself off omeprazole and, if I have a stomach ache or heartburn, I drink the small amount of vinegar in water, or have a little coriander in water or I have some sauerkraut. I know she might not be at a place to eat that, though.

Sending this with a prayer for your daughter and you.

Cathy

antelope1225
Name: Cathy1225
Who do you know with myeloma?: Myself
When were you/they diagnosed?: May 25 2012
Age at diagnosis: 55

Re: What nausea medications work?

by Joneman on Fri Aug 21, 2015 9:42 pm

I won't repeat the oral medications mentioned earlier; mostly they work fine. However, I haven't seen anyone mention IV anti-nausea medications. Have you tried an IV med prior to the chemo infusion? I did that with Kyprolis and it worked wonders in keeping the nausea from developing. If I need more at home, then Compazine works for me.

Joneman

Re: What nausea medications work?

by Claud488 on Fri Aug 21, 2015 11:09 pm

Ondansetron 8 mg (known as: Zofran) has been working well for me.

For what it's worth, I'm starting 5th cycle of Revlimid, Velcade, and dex (RVD) (2 weeks on, 1 week off) of my induction. I did not experience any nausea until about 3rd cycle. Now I get it oc­ca­sion­ally, but the prescription takes care of it.

Claud488
Name: Claud
Who do you know with myeloma?: Me
When were you/they diagnosed?: April, 2015
Age at diagnosis: 67

Re: What nausea medications work?

by Jasmine on Sat Aug 22, 2015 1:25 am

Periactin (cyproheptadine) worked for my husband when none of the above worked.

Good luck and hang in there. My husband has been back to work for 4 years and on no meds and only side effect is peripheral neuropathy, which no longer annoys him. It took him 6 weeks to get any energy after stem cell transplant, then one morning he woke up his old self and has never gone back. I wish someone had let me know that it us possible to get back to normal life when we were going through everything.

One day at a time – it will be worth it .

Jasmine

Re: What nausea medications work?

by RadiantTiger on Sat Aug 22, 2015 2:50 pm

Wondering if anyone has personal experience with cannabidiol products. Multiple people have recommended this to me for post transplant chemo nausea and lack of appetite. I bought some, but have not tried it yet. (Transplant pending in October).

Ginger is good. Zofran causes constipation, which I want to avoid.

RT

RadiantTiger
Name: Radiant Tiger
Who do you know with myeloma?: Myself, my deceased uncle
When were you/they diagnosed?: Feb 2015
Age at diagnosis: 54

Re: What nausea medications work?

by Bar-none on Wed Aug 26, 2015 8:41 pm

Hi All,

For mild nausea I also use crystalized ginger. It's readily available at many stores and online and works great for me. Today I dropped a little fresh ginger root in my smoothie which gave it a nice spice!

Best to all! BN

Bar-none
Who do you know with myeloma?: Me
When were you/they diagnosed?: 3/14

Re: What nausea medications work?

by antelope1225 on Thu Aug 27, 2015 10:06 pm

I never thought of ginger in my smoothie - great idea.

I usually have ginger as tea - you can buy a ginger root and slice it in thin slices and steep that in hot water for a while.

Cathy

antelope1225
Name: Cathy1225
Who do you know with myeloma?: Myself
When were you/they diagnosed?: May 25 2012
Age at diagnosis: 55

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