I'm on my second cycle of Pomalyst and dexamethasone (20 mg). After the first cycle, I gained 5 pounds, had big weekly swings in energy and mood, etc.
Since I have access to a blood sugar meter tester, I checked and found the dex made me have much higher than normal blood sugars (instead of normal 80's I was going over 140 and up).
I switched to a low-carb diet (stay near / under 25-30 carbs per meal, under 10 for breakfast). Weight is now back to starting weight after a couple of weeks. Energy and mood leveled out also. I feel so much better. Water retention is gone. Pretty simple solution for me, hope it keeps working.
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