The question I have that may change my answer has to do with your current treatment. If you are on treatment with steroids, I would not get the MMR vaccine. I know you haven't had a transplant, but we are giving our patients the MMR vaccine two years after transplant even if they are on maintenance Revlimid. So, if you are on Revlimid, the MMR vaccine should be ok.
It's ok to go ahead with the inactivated typhoid shot (not the oral).
And it's ok to get the hep A and B, tetanus, and inactivated polio vaccines.
The yellow fever vaccine is a live virus, so my recommendations are the same as the MMR vaccine.
I would be surprised if they recommended the rabies vaccine without a known exposure.
Most importantly, I would speak to a travel medicine specialist as well as your myeloma physician.
Africa is BIG, and it would help to know where you intend to go.
As for anti-malarials, it's also best to be specific about the location. I prefer Lariam (mefloquine hydrochloride) – it's once a week and, if I take it in the evening, I get weird dreams and a slightly off day. It's also a good anti-malarial for Tanzania and Kenya, which is where I usually am.
Yellow fever certificates are required for some border crossings. If you're staying within a country, flying in and out from Europe, you shouldn't need it. If you're crossing from Kenya to Tanzania, you might be required to present it or pay a bribe.