[PalmerDJ]

Urine test results - how concerned should I be?

by PalmerDJ on Thu Jan 28, 2016 8:59 pm

64-year old with recent tests that look like those posted below. Never saw my blood work come back like this. How concerned should I be? I am extremely fearful.

Official lab test results report
Date of Service: Jan 22, 2016, 3:00 PM
Attachment Original lab test results (1/27/2016 1:11:26 PM).pdf

Lab Test Results
ife+protein electro, 24-hr ur

Immunofixation result, urine

Immunofixation shows IgA monoclonal protein with lambda light chains specificity and mono­clonal free lambda light chains (Bence-Jones Protein).

M-spike, mg/24 hr 1332 Not Observed mg/24 hr
M-spike, % 37.4 Not Observed %
Gamma globulin, u 39.4 %
Beta globulin, u 13.4 %
Alpha-2-globulin, u 3.3 %
Alpha-1-globulin, u 2.0 %
Albumin, u 41.9 %
Prot,24hr calculated 3561.0 30.0-150.0 mg/24 hr
Protein,total,urine 237.4 0.0-15.0 mg/dL

[3334]

Re: Urine test results - how concerned should I be?

by 3334 on Tue Feb 02, 2016 10:19 am

PalmerDJ,

3561 mg of urinary protein in a 24-hour specimen is very high. Are you seeing a kidney specialist to evaluate your kidney function?

Nephrotic syndrome is a serious medical condition with different causes. A kidney biopsy was recommended by my myeloma specialist when the urinary protein kept climbing. It got to about 2300 mg per 24-hour in March 2015. The kidney biopsy results came back positive for renal amyloidosis.

Revlimid, Velcade, and dexamethasone for 5 months followed by a stem cell transplant October 16, 2015 brought the 24-hour urine protein down to 300 mg. Serum kappa light chains reduced from a high of 10,980 mg/L to 37.4 mg. The bone marrow neoplastic plasmacytosis also reduced from 80% to 5% after induction treatment and then autologous stem cell transplant.

This month I start maintenance Velcade subcutaneous every other week for 2 years. I returned to work last week and feel great.

Hopefully your urinary protein will come down soon.

Good luck.
Margo