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Anyone with both lambda and kappa M-spikes?
I have both lambda and kappa proteins showing up in my M spike numbers. My blood work showed a lambda M-spike of 0.51 and a kappa spike of 0.60 giving me a total of 1.10, I was told it was extremely rare but not more dangerous because the chemo will attack both lambda and kappa.
Re: Anyone with both lambda and kappa M-spikes?
Did you have myeloma before? Or is this your first diagnosis? What is your M-spike?
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KMZ - Who do you know with myeloma?: Mother
- When were you/they diagnosed?: June 2013
- Age at diagnosis: 76
Re: Anyone with both lambda and kappa M-spikes?
f cancer,
It sounds like you just started induction treatment (or are just about to), and you haven't had a transplant.
You don't spell out the entire isotype. Which immunoglobulin(s) (IgG, IgA, etc) are the lambda and kappa M-spikes associated with?
This could be either a case of biclonal gammopathy or oligoclonal gammopathy (your doc would need to make that call by looking at your SPEP, IFE and various blood tests).
To find other patients with this condition, you can use the advanced search function on this forum and search on "biclonal" and "oligoclonal", limiting the search to message text only.
In general, my understanding is that there is not an additionally adverse prognosis for a newly diagnosed multiple myeloma patient that is found to have a biclonal gammopathy versus a monoclonal gammopathy. They are both treated the same way. At least, that is what I recall in my various readings.
It sounds like you just started induction treatment (or are just about to), and you haven't had a transplant.
You don't spell out the entire isotype. Which immunoglobulin(s) (IgG, IgA, etc) are the lambda and kappa M-spikes associated with?
This could be either a case of biclonal gammopathy or oligoclonal gammopathy (your doc would need to make that call by looking at your SPEP, IFE and various blood tests).
To find other patients with this condition, you can use the advanced search function on this forum and search on "biclonal" and "oligoclonal", limiting the search to message text only.
In general, my understanding is that there is not an additionally adverse prognosis for a newly diagnosed multiple myeloma patient that is found to have a biclonal gammopathy versus a monoclonal gammopathy. They are both treated the same way. At least, that is what I recall in my various readings.
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Multibilly - Name: Multibilly
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Smoldering, Nov, 2012
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