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Trouble interpreting bone marrow biopsy results

by Wayne K on Tue Mar 04, 2014 7:35 pm

Can anyone make some sense of this for me? This was made with CLL as the target.

I originally started seeing my hematologist/oncologist for CLL and it was during a biannual visit that my multiple myeloma was detected.

Analysis: CD45, side scatter and CD45, CD71 screening plots identify 7.2% lymphocytes, 5.1% monocytes, 61.2% granulocytes, 2.7% blasts and 19.1% erythroid precursors. 4.2% of cells coexpress CD13 and CD34. Gated brightly CD45 positive lymphocytes are 66.2% CD3 positive T cells, 19.8% CD19 positive B cells, and 14.0% CD3 and CD19 negative cells consistent with natural killer cells. Gated B cells are positive for CD5, CD23, and lambda light chain and negative for FMC-7 and kappa light chain.

Wayne K
Name: Wayne
Who do you know with myeloma?: Myself, my sister who passed in '95
When were you/they diagnosed?: 03/09
Age at diagnosis: 70

Re: Trouble interpreting bone marrow biopsy results

by Dr. Jason Valent on Thu Mar 06, 2014 10:36 am

"Gated B cells are positive for CD5, CD23, and lambda light chain and negative for FMC-7 and kappa light chain."

More consistent with CLL than myeloma.

Dr. Jason Valent
Name: Jason Valent, M.D.
Beacon Medical Advisor

Re: Trouble interpreting bone marrow biopsy results

by Wayne K on Thu Mar 06, 2014 6:17 pm

The BMB was ordered to see where my multiple myeloma is at this point. My Lambda light chains are rising and I had a clavicle break at a lesion. I'm assuming who ever ordered it looked at my records briefly and thought he was back to my CLL. Does this information give him enough to know what involvement I have now?
I won't see him for a couple of weeks and frankly I'm a little anxious. Thanks.

Wayne K
Name: Wayne
Who do you know with myeloma?: Myself, my sister who passed in '95
When were you/they diagnosed?: 03/09
Age at diagnosis: 70


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