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Discussion about multiple myeloma treatments, stem cell transplants, clinical trials, alternative medicines, supplements, and their benefits and side effects.

Definition of "rounds" and "cycles" of treatment

by SBarro on Sun Dec 21, 2014 11:06 am

In this forum, I often come across the use of the words "rounds" and "cycles" of treatment, but without mention of the number and / or frequency of treatment. I looked for a glossary of terms, but couldn't find any definition, though it appears that these are common terms.

Can someone please explain these terms?

Thanks,
Tom

SBarro
Name: Thomas Tonon
Who do you know with myeloma?: myself
When were you/they diagnosed?: April, 2014
Age at diagnosis: 69

Re: Definition of "rounds" and "cycles" of treatment

by NStewart on Sun Dec 21, 2014 9:10 pm

I consider a round of treatment in my regimen as a 28 day cycle. I am taking Revlimid for 21 days and then have 7 days off. This equals 28 days or 1 round for me.

Nancy in Phila

NStewart
Name: Nancy Stewart
Who do you know with myeloma?: self
When were you/they diagnosed?: 3/08
Age at diagnosis: 60

Re: Definition of "rounds" and "cycles" of treatment

by Ian on Mon Dec 22, 2014 6:55 am

I always consider "round" and "cycle" to mean the same thing. Here is the U.S. National Cancer Institute's definition of a treatment cycle:

"In medicine, a course of treatment that is repeated on a regular schedule with periods of rest in between. For example, treatment given for one week followed by three weeks of rest is one treatment cycle."

http://www.cancer.gov/dictionary?cdrid=688840

For many myeloma treatment regimens, a 4-week (28-day) cycle is common. So when someone says that they have had 4 "rounds" or "cycles" of treatment, they are talking about approximately 4 months of treatment.

There are exceptions, however, to the 4-week norm, often involving treatment with Velcade, which can be given in cycles that are shorter or longer than 4 weeks.

Ian

Re: Definition of "rounds" and "cycles" of treatment

by K_Shash on Wed Dec 24, 2014 11:07 pm

My Revlimid Instructions have this heading: "7 days before ordering the 'next supply" (or next cycle start date)," implying the three-week therapy (and the week off) are the "cycle."

I just came across this while going over the next few weeks blood tests, appointments, and surveys I have to complete. I hope this helps.

This definition seems to agree with what others have said.

K_Shash

K_Shash
Name: K_Shash
Who do you know with myeloma?: Self
When were you/they diagnosed?: November 2014
Age at diagnosis: 67

Re: Definition of "rounds" and "cycles" of treatment

by Wayne K on Fri Dec 26, 2014 2:45 pm

I'm on the same schedule with Revlimid. When I was taking my original Velcade treatment, I also had a resting period after a series of prednisone and Velcade. I don't recall specifically what the doctor called them, but they were "rounds" or "cycles".

Wayne K
Name: Wayne
Who do you know with myeloma?: Myself, my sister who passed in '95
When were you/they diagnosed?: 03/09
Age at diagnosis: 70


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