[GoDucks]

Switching from CyBorD to RVD

by GoDucks on Wed Jun 07, 2017 1:29 am

I have been tracking blood counts, plasma, M-spike, etc since last July when my PCP noticed I was slightly anemic and referred me to hematology oncology. Probably nothing, could be something.

Fast forward to March, diagnosed with IgG kappa multiple myeloma after bone marrow biopsy and ended up in hospital for 4 days with multiple bilateral PE. That was the scariest part.

Since then, I've completed 3 cycles of CyBor D (cyclophosphamide, Velcade, and dexa­metha­sone) with minimal side effects. I've also had minimal results, M-spike down from 2.75 to 1.99 g/dL (27.5 to 19.9 g/l). Bone marrow biopsy results in March showed 35% plasma cells, 2 small lesions after PET scan. Other than that, no new bone pain, and my M-spike, light chains, and IgG levels are pretty much what they were back in September before treatment. Hemoglobin and RBC, as well as WBC low, partial symptom, partial treatment effect.

I'll be switching to Revlimid, Velcade, and dexamethasone (RVD) induction next week. I am wondering what to expect in terms of how effective the different treatment will be, and what sort of different side effects there may be. Hope I can roll with any side effects and get better results. As all my docs say, " I'm otherwise young and healthy."