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Re: Subcutaneous Velcade - "air bubble" technique

by Beacon Staff on Wed Sep 09, 2015 10:20 am

Hi Robert,

Here is a summary of the technique that we've developed based on several sources, the main one being the one listed below. Perhaps you can just share a link to this thread with the nurses so that they have the patient experiences, this summary, and an additional reference all in one place..

The technique is as follows:

  1. Attach a fresh needle (4-6 millimeter) to syringe with prepared medication
  2. Do not purge needle (air in needle)
  3. Draw the Velcade into the syringe for a maximum volume of 2 ml medication per site for subcutaneous injection
  4. Pull 0.5-1.0 ml air into syringe, so that the is behind the drug when the syringe is inverted
  5. Using the index finger and thumb, "pinch an inch" in the selected site for injection; avoid pinching the underlying muscle
  6. Invert syringe, inject at 90 degree angle for needles 4-6 millimeter, and at 45 degree angle for needles 8 millimeters or longer, including air behind the drug, which effectively seals the drug into the subcutaneous fat (preventing it from leaking into the surrounding tissue)
  7. Remove needle promptly
  8. Apply gentle pressure to site.
This summary is based mainly on information from this article:

Kurtin et al, "Subcutaneous Administration of Bortezomib: Strategies to Reduce Injection Site Reactions," Journal of the Advanced Practitioner in Oncology, Nov-Dec 2012 (full text of article at PubMed)

which also has a helpful table summarizing the technique and related information. However, additional information from other sources also has been used to make the summary above as clear as possible.

Beacon Staff

Re: Subcutaneous Velcade - "air bubble" technique

by Robert on Wed Sep 09, 2015 6:05 pm

Thank you so much! The summary makes this very clear, and the journal reference adds credibility.

Robert

Re: Subcutaneous Velcade - "air bubble" technique

by seebee on Fri Sep 11, 2015 11:22 am

My reactions to Velcade injections are always a big welt (3 x 4 inches) that burns and itches start­ing 2nd or 3rd day and lasts for 3 days. Sometimes it "spiders" out inches in different di­rec­tions. Very hard to ignore – especially the burn / itch!

The air bubble method as described above is definitely helpful and reduces the intensity and dur­a­tion of the itch. Some tenderness still last 4-5 days, but I hardly notice it.

My integrative oncologist also recommended arnica ointment before the injection and con­tinu­ing 3x per day afterward. I think this speeds healing. Cortisone does not seem to do anything for me. Skin is red - sometimes bruised - for 3 weeks. With the air bubble technique and arnica, I get by!

My oncologist asked about going back to infusion, but I already have peripheral neuropathy and would rather put up with the welts. Not everyone has such severe reactions, but if you do, be sure to ask / push for the bubbles!

seebee

Re: Subcutaneous Velcade - "air bubble" technique

by kemscm on Tue Jun 06, 2017 1:15 pm

Thanks so much for the link to the article. I will be getting my first Velcade shot tomorrow and, if I have a reaction, I think I will print off Table 2 from the article and take it with me. Then I'll tell them my stepdaughter was an oncology nurse (she's now a doctor) and she recommended this method to keep it off my skin.

I've lived long enough to figure out that approaching people with a personal story often works better than "I read this online." ;) Just tell 'em you have a friend who's a nurse.

kemscm
Name: Kate
Who do you know with myeloma?: Me (possibly)
When were you/they diagnosed?: In process
Age at diagnosis: 63

Re: Subcutaneous Velcade - "air bubble" technique

by Gala on Thu Jun 08, 2017 11:40 pm

I have a question.

The technique described above states:

  1. Attach a fresh needle (4-6 millimeter) to syringe with prepared medication
  2. Do not purge needle (air in needle)
  3. Draw the Velcade into the syringe for a maximum volume of 2 ml medication per site for subcutaneous injection
It sounds like there is medication in the syringe already and then we have to draw some Velcade in. At what point do we draw the Velcade into the syringe, before or after changing the needle?

Gala
Name: Gala
Who do you know with myeloma?: sister, LgA-k
When were you/they diagnosed?: December 2015
Age at diagnosis: 48

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