Here is a summary of the technique that we've developed based on several sources, the main one being the one listed below. Perhaps you can just share a link to this thread with the nurses so that they have the patient experiences, this summary, and an additional reference all in one place..
The technique is as follows:
- Attach a fresh needle (4-6 millimeter) to syringe with prepared medication
- Do not purge needle (air in needle)
- Draw the Velcade into the syringe for a maximum volume of 2 ml medication per site for subcutaneous injection
- Pull 0.5-1.0 ml air into syringe, so that the is behind the drug when the syringe is inverted
- Using the index finger and thumb, "pinch an inch" in the selected site for injection; avoid pinching the underlying muscle
- Invert syringe, inject at 90 degree angle for needles 4-6 millimeter, and at 45 degree angle for needles 8 millimeters or longer, including air behind the drug, which effectively seals the drug into the subcutaneous fat (preventing it from leaking into the surrounding tissue)
- Remove needle promptly
- Apply gentle pressure to site.
Kurtin et al, "Subcutaneous Administration of Bortezomib: Strategies to Reduce Injection Site Reactions," Journal of the Advanced Practitioner in Oncology, Nov-Dec 2012 (full text of article at PubMed)
which also has a helpful table summarizing the technique and related information. However, additional information from other sources also has been used to make the summary above as clear as possible.