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General questions and discussion about multiple myeloma (i.e., symptoms, lab results, news, etc.) If unsure where to post, use this discussion area.

stem cell transplant

by Kate on Thu Oct 11, 2012 10:09 am

I need your expertise.. My husband was diagnosed almost two years ago. He took rev. and dex. and that put him in remission for a year. He recently relapsed and the doctors are suggesting a stem cell transplant. Docs at MD Anderson say that this has become standard treatment. What are your thoughts and opinions? My husband is very young. 42. Should we wait until all meds stop working. Should we nip it in the bud now? He is responding very well to this new round of treatment. Please help us with this decision.

Katie

Kate

Re: stem cell transplant

by Gilsiegel on Thu Oct 11, 2012 2:30 pm

63 years old non-secretory guy
2 transplants in 2010 my own cells collected 22 million over 2 days
Great response difficult times physically and mentally during but now I am very active and feel good.keep moving and exercise to the max
Trust the staff and get it done!

Gilsiegel

Re: stem cell transplant

by Snip on Thu Oct 11, 2012 6:55 pm

Tough question.

I had it done just over a year ago, and it worked out OK. Ended up with what they categorize as a 'very good partial response', which was good... and permanent heart damage, which was not so good. It's a back-and-forth discussion out in the field these days, for sure... do your research and make up your own minds on this. ASCT is a knife that cuts both ways, but then so are all the novel treatments.

Snip
Name: John Snippe
Who do you know with myeloma?: me
When were you/they diagnosed?: Jan, 2011
Age at diagnosis: 56

Re: stem cell transplant

by Dr. Peter Voorhees on Fri Oct 12, 2012 2:07 am

Dear Katie,

Autologous stem cell transplantation (also known as high-dose chemotherapy with stem cell rescue) is one of many standards of care in multiple myeloma. This is based on phase 3, randomized studies showing the benefits of this approach. With your husband being 42, I would be a proponent of taking advantage of all of the weapons available at your disposal for this disease. If you decide to go with high-dose chemotherapy, I would do it sooner rather than later. It is harder to tolerate and leads to disappointingly short remissions when done as a last ditch effort after all else has failed. If, after learning about the potential benefits and risks of this approach, you decide to go for it, I would do it now.

Good luck and let us know what you decide to do!

Pete V.

Dr. Peter Voorhees
Name: Peter Voorhees, M.D.
Beacon Medical Advisor


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