Brandy, G-CSF is Neupogen. My care team likes to call it the "G-Shot".
With my M-spike at 0.1, I was borderline concerning additional chemo, with my team initially planning to give me several consecutive days of chemo followed with the G shot. But they determined to go ahead with harvest without extra induction. If my 0.1 was on the border, then your 0.08 may have been in the acceptable range.
Forums
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StandingTall - Who do you know with myeloma?: Me! yay!!
- When were you/they diagnosed?: Sept. 2013
- Age at diagnosis: 39
Re: Stem cell harvest without inital chemo
Hi Brandy.
I had several months of Velcade and Dex. Gave myself the Neupogen shots for 5 days and then did the harvest through my arms in about 5 1/2 hours. I had no Chemo before harvest. Had Melphalan and then the transplant. Happy to say after a few months I reached CR.
I had several months of Velcade and Dex. Gave myself the Neupogen shots for 5 days and then did the harvest through my arms in about 5 1/2 hours. I had no Chemo before harvest. Had Melphalan and then the transplant. Happy to say after a few months I reached CR.
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Guitarnut - Name: Scott Hansgen
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Sept 2011
- Age at diagnosis: 47
Re: Stem cell harvest without inital chemo
Ok, thanks Brandy. That clarifes your question.
GCSF stands for granulocyte stimulating factor (Neupogen). Regarding your question you are not losing any benefits of the transplant by having your stem cell collection done without cyclophosphamide. Collection is routinely done with or without cyclophosphamide.
GCSF stands for granulocyte stimulating factor (Neupogen). Regarding your question you are not losing any benefits of the transplant by having your stem cell collection done without cyclophosphamide. Collection is routinely done with or without cyclophosphamide.
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Dr. Edward Libby - Name: Edward Libby, M.D.
Beacon Medical Advisor
Re: Stem cell harvest without inital chemo
Thank you for providing so many information of SCT, Dr. Libby.
When stem cells are harvested from multiple myeloma's patient for a SCT candidate, are the myeloma cancer cells screened out of these stem cells? If not, then the multiple myeloma's patient still carries these bad genes carrying markers such as CD38, CD44...etc. in side of these harvest stem cells without filtering out these cancer cells. Also these bad cells will cause the relapse of multiple myeloma in future again.
Our BMT doctors mentioned that they does not have a technology to filter out these bad cells, so we would wait a SCT until relapse, and SCT will perform after a lot of deep and heavy chemotherapies to wipe out own body of immune system with serious side effects outside of hospital for several day. So far we have harvested stem cells in reservation after having Neupogen and Mozobil , we do plan to perform a SCT if we have to do it.
She was diagnosed as extramedullary Plasmacytoma on both pancreatic organ and pelvic with a negative Multiple Myeloma on bone marrow, and these tumors disappeared after having RVD treatments and three times of CT scans. Hematology oncologists and BMT Doctors strongly recommend to have ASCT after fifth cycle on July, 2011. Now she have performed maintenance chemotherapies since May 2012.
When stem cells are harvested from multiple myeloma's patient for a SCT candidate, are the myeloma cancer cells screened out of these stem cells? If not, then the multiple myeloma's patient still carries these bad genes carrying markers such as CD38, CD44...etc. in side of these harvest stem cells without filtering out these cancer cells. Also these bad cells will cause the relapse of multiple myeloma in future again.
Our BMT doctors mentioned that they does not have a technology to filter out these bad cells, so we would wait a SCT until relapse, and SCT will perform after a lot of deep and heavy chemotherapies to wipe out own body of immune system with serious side effects outside of hospital for several day. So far we have harvested stem cells in reservation after having Neupogen and Mozobil , we do plan to perform a SCT if we have to do it.
She was diagnosed as extramedullary Plasmacytoma on both pancreatic organ and pelvic with a negative Multiple Myeloma on bone marrow, and these tumors disappeared after having RVD treatments and three times of CT scans. Hematology oncologists and BMT Doctors strongly recommend to have ASCT after fifth cycle on July, 2011. Now she have performed maintenance chemotherapies since May 2012.
Last edited by chen5631867 on Wed Feb 26, 2014 12:19 am, edited 1 time in total.
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chen5631867 - Name: George Chen
- Who do you know with myeloma?: My Spouse
- When were you/they diagnosed?: Feb. 25, 2011
- Age at diagnosis: 53
Re: Stem cell harvest without inital chemo
Hi chen5631867,
There has been research done about the possibility of treating collected stem cells to remove whatever remaining myeloma cells may be among them. You can read more about this research, including its current status, in this forum discussion from last November:
https://myelomabeacon.org/forum/treating-collected-stem-cells-to-kill-myeloma-cells-t2512.html
There has been research done about the possibility of treating collected stem cells to remove whatever remaining myeloma cells may be among them. You can read more about this research, including its current status, in this forum discussion from last November:
https://myelomabeacon.org/forum/treating-collected-stem-cells-to-kill-myeloma-cells-t2512.html
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