[Ravi]

Have progressed after solitary bone plasmacytoma

by Ravi on Sat Feb 28, 2015 11:41 am

Hi mates,

I experienced severe back pain during mid 2010. In March 2011, my neurosurgeon told me I am suffering from a solitary bone plasmacytoma and the plasmacytoma was at D2 . My bone marrow aspirate and biopsy results were negative (plasma cell count less than 5). My blood results were normal.

The treatment given was surgery with radiation therapy (RT) of 50 Gy over 25 sessions

Again, I started experiencing severe back pain by mid 2014. In December 2014, an MRI showed a second plasmacytoma at D6. My blood results were normal except for kappa, which was 22.3. Bone marrow aspirate and biopsy were also negative (plasma count less than 5).

This time, the treatment was laminectomy at D6 and partial laminectomy at D5. RT of 50 Gy over 25 sessions.

I had a PET scan before RT, which showed lesion at D6 and a small lesion on the left 5th rib.
So, my oncologist told me I have progressed to multiple myeloma.

He has started with Revlimid (15 mg) for 1st month, with 25 mg for 2nd and 3rd months. And dexamethasone once every week.

I have no CRAB features (except for two body lesions) and my protein level is normal. But my kappa value is 22.3

I just want to know where do I stand and what could I expect?

[Dr. Jonathan Kaufman]

Re: Have progressed after solitary bone plasmacytoma

by Dr. Jonathan Kaufman on Sun Mar 01, 2015 6:42 pm

Typically, patients who are diag­nosed with multiple myeloma after originally having a solitary plasma­cy­toma do not have different outcomes from patients whose first myeloma-related diagnosis is symptomatic multiple myeloma. For the most part, how you will do depends on the myeloma risk status, stage and response to treatment.

I wish you the best,

Jlk