[rumnting]

Side effects - Pomalyst, Kyprolis & dex regimen?

by rumnting on Tue Nov 11, 2014 10:25 pm

My husband was switched from RVD [Revlimid, Velcade, dexamethasone] (became ineffective) and is on his 5th week of Pomalyst (4mg per day), Kyprolis, and dex.

His hemoglobin is ok at this time. He is having bad bouts of extreme lightheadedness. It has only happened at home, so his blood pressure has not been checked during these episodes. His pulse is not elevated. He is not sweaty. He just has to lie down or he feels like he will pass out. His local oncologist is on a medical leave for 3 months. There is only one other patient in the practice on these meds.

Has anybody else had these symptoms?

[Multibilly]

Re: Side effects - Pomalyst, Kyprolis & dex regimen?

by Multibilly on Tue Nov 11, 2014 10:34 pm

Rumnting,

Home blood pressure monitors are pretty inexpensive these days and you can find them just about everywhere, including Walmart. Just a thought if you want to verify if the lightheadedness is due to a drop in blood pressure. You can also always return the unit for a refund it if you find it isn't the cause.

Also, note that "lightheadedness" is specifically called out in both of these posts:

http://www.drugs.com/sfx/pomalyst-side-effects.html

http://www.drugs.com/kyprolis.html

[Dad from San Diego]

Re: Side effects - Pomalyst, Kyprolis & dex regimen?

by Dad from San Diego on Tue Apr 28, 2015 4:16 am

I had significant trouble with lightheadedness and dizziness as well. Several times I had to lay down and raise my feet until it passed. And several times I cancelled planned activities. And, while joining a friend at a cancer center (not my own) for lunch, I fainted right into the arms of a nurse. Many physicians, nurses, medical and emergency personnel attended to me. Perhaps it was because I kept losing and regaining consciousness and losing and regaining measurable blood pressure, they decided to transport me by ambulance to emergency. No one was able to determine what caused this.

Because I had grade 3 anemia and grade 4 neutropenia even after reducing dosage, no one paid much attention to my complaints of lightheadedness and dizziness, or my blood pressure for that matter until it was measured at 83/47 at a blood transfusion. Now, I'm using a different drug.

I have a blood pressure monitor at home but never thought my problems were associated with blood pressure. Now I know to monitor my BP when I change medications.