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Questions and discussion about monoclonal gammopathy of undetermined significance (i.e., diagnosis, risk of progression, living with the disease, etc.)

Shingles & risk of developing MGUS

by ricejon on Sun Jun 04, 2017 7:06 am

Hello folks,

Is there any known link between shingles and MGUS? For example, if you've had shingles, are you at a greater risk of developing MGUS?

I had shingles in 2003 and I was diagnosed with MGUS in 2016. I am dealing with peripheral neuropathy and leg weakness now.

Thank you in advance.

ricejon
Name: Jon
Who do you know with myeloma?: mgus (self)
When were you/they diagnosed?: 2016
Age at diagnosis: 47

Re: Shingles & risk of developing MGUS

by Multibilly on Sun Jun 04, 2017 3:17 pm

Jon,

You should read this paper:

Lindqvist, EK, et al, "Personal and family history of immune-related conditions increase the risk of plasma cell disorders: a population-based study," Blood, Dec 8 2011 (full text of article)

Excerpt:

"A significantly elevated risk of MGUS was found in patients with a history of pneumonia, intestinal infection, gonorrhea, septicemia, herpes zoster [shingles], pyelonephritis, cystitis, sinusitis, rhinitis, influenza, meningitis, Lyme disease, pericarditis, myocarditis, endocarditis, empyema, and erysipelas."

Multibilly
Name: Multibilly
Who do you know with myeloma?: Me
When were you/they diagnosed?: Smoldering, Nov, 2012

Re: Shingles & risk of developing MGUS

by ricejon on Mon Jun 05, 2017 4:32 pm

Thank you very much for the reply, MultiBilly!

ricejon
Name: Jon
Who do you know with myeloma?: mgus (self)
When were you/they diagnosed?: 2016
Age at diagnosis: 47


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