[Cindy1]

Serum electrophoresis result

by Cindy1 on Fri Oct 12, 2012 2:40 pm

Hi all,
My PCP sent me for a immunoglobulin G,A,M and serum electrophoresis tests.The results came back as follows;
Immunglobulin G 11 (6-15)
Immunoglobulin A 1.91 (0.7-4)
Immunoglobulin M 0.74 (0.5-2.3)

SPE:There is a small IgG restriction in the gamma fraction.No monoclonal protein band detected.They suggest a repeat test in 3-6 months to monitor.

What does this mean?.I am a thirty two year old female.I have ongoing trouble with anaemia,fatigue and joint pain.
Thank You

[Dr. Adam Cohen]

Re: Serum electrophoresis result

by Dr. Adam Cohen on Mon Oct 15, 2012 5:35 pm

Dear Cindy1,
Your immunoglobulin levels appear to be within the normal range, and your SPEP results are equivocal, with a questionable monoclonal protein (IgG) seen that isn't even measurable. Based on your symptoms and your demographics, I would ask your PCP if he/she is working you up for an autoimmune disease, which can sometimes be associated with low-level abnormalities on SPEP or other myeloma screening tests.
Best regards,
Adam Cohen

[Cindy1]

Re: Serum electrophoresis result

by Cindy1 on Fri Oct 19, 2012 3:16 pm

Thank you foryour reply.I have had many auto immune tests,some positive.My PCP is going to refer me to a haematologist for further tests.Thanks again.