[chinnadu92]

Is remission after failed allogeneic transplant possible?

by chinnadu92 on Thu Aug 09, 2018 1:36 pm

Hi everybody

Recently (February) 2018) my mom completed an allogeneic stem cell transplant. Unfortunately the disease relapsed again in July. Is there any possibility of getting remission?

[Multibilly]

Re: Is remission after failed allogeneic transplant possible

by Multibilly on Thu Aug 09, 2018 9:15 pm

Hi Chinna,

Welcome to the forum. I'm sorry to hear that your mom's allogeneic stem cell transplant ("allo") wasn't successful.

You don't say what drug regimens your mom tried before she had her allo. In general, allos tend to have better success with those patients that haven't been heavily pre-treated. Again, I don't know what drugs your mom tried in the past, but there are many new therapies out there, including various monoclonal antibody treatments that have led to fairly durable, complete responses for quite a few patients.

But keep in mind that most everyone that is on a drug treatment program to hold their myeloma at bay will likely relapse or have disease progression at some time in the future. At that time, they need to reinstate their treatment or try a new drug regimen. Permanent remission (i.e. something approaching a "cure") usually does not occur in myeloma patients, except for those patients that have had successful allogeneic transplants.