[juliepost30]

Possible Multiple Myeloma

by juliepost30 on Mon May 27, 2013 4:55 pm

Hello everyone!

Just need some advice. I had Liver Failure on 4/6/2013 and all liver enzymes as well as a few other tests were way out of wack. I don't drink so that is not what happened and I do not do any illicite drugs. So, anyway back to the Liver Failure, they are not sure what caused it. I have read that Multiple Myeloma can affect all organs of the body especially the kidney's, liver and bones. As I said all liver enzymes were elevated as well as bone markers such as Alkaline Phosphase which was 400 and now down to 155. Bilirubin/globulin was low, calcium low. Well I noticed a trend of these fluctuating over the past two years as I have blood tests from the past two years. At one point I had low red blood cells and through x-rays done of spine from me complaining of bone pain they found that I have sclerosis starting in my spine. The most recent CT scan I had done showed 10 kidney stones, a slightly enlarged liver, common bile duct enlargement, fluid in my uterin cavity and a Focal Bone Lesion on my left iliac crest possibly a bone island. Also, I always get pneumonia, kidney and bladder infections as well as sinus infections.

Should I speak with my doctor about this maybe being Multiple Myeloma??? Thank you for the advice.

[Ron Harvot]

Re: Possible Multiple Myeloma

by Ron Harvot on Wed May 29, 2013 11:31 pm

If you think you have multiple myeloma then by all means talk to your doctor and voice your concerns. Ask him to run blood and urine tests to see if you have an M spike or other indications. At the very least you can eliminate this as a possible cause for your liver problems.

Ron

[Dr. Ken Shain]

Re: Possible Multiple Myeloma

by Dr. Ken Shain on Sat Jun 01, 2013 9:36 am

Liver failure or even toxicity would be a rare event in the presentation of multiple myeloma. I would suggest that other etiologies are more likely. This is not to say the multiple myeloma or associated plasma cell disorders cannot be associate. These would typically be primary amyloidosis and LCDD (light chain deposition dieseas).

In your case, of fluctuating results (up and then back to normal) makes it difficult to think this related to a plamsa cell disorder at this time. These are more likely to be progressive in nature- only getting worse.

It will be important to continue to monitor carefully and that your physician(s) keep an eye out and an open mind. If there is further evidence in your laboratory findings- elevated total protein, elevated globulin, anemia, renal insufficiency, elevated calcium, low albumin- these would be more suggestive of a potential myelomatous process. However, you can always ask your MD to order myeloma labs if there is reasonable to data to do so.

Best of luck and please keep us informed.