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Discussion about multiple myeloma treatments, stem cell transplants, clinical trials, alternative medicines, supplements, and their benefits and side effects.

Pomalyst, Cytoxan, and dex side effects?

by blustein on Thu Feb 19, 2015 11:23 am

How are those on Pomalyst, Cytoxan, and dex doing? I am starting my second cycle and it has been more difficult than the first round. Results so far are good, but the side effects have been more noticeable this time around. Fatigue and nausea have been the biggest problem so far.

I would be curious to hear how others using this regimen are faring.

blustein
Name: Richard Blustein
Who do you know with myeloma?: Self
When were you/they diagnosed?: July 2009
Age at diagnosis: 58

Re: Pomalyst, Cytoxan, and dex side effects?

by KWeisman on Thu Feb 19, 2015 6:57 pm

Hi Richard,

I haven't been on pomalidomide, but I found a good way to avoid nausea from oral Cytoxan (I was on CyBorD). I would take a single ondasetron (Zofran). Then, 30 minutes later, I would eat a third of a package of mashed potatoes as a buffer. Then I would take my 11 Cytoxan tablets with a big glass of water. This really kept the nausea to a minimum.

I did it for 3 out of 4 weeks for 8 months.

Best,
Katie

KWeisman
Who do you know with myeloma?: Myself
When were you/they diagnosed?: 12/2012
Age at diagnosis: 47

Re: Pomalyst, Cytoxan, and dex side effects?

by gfcocala on Thu Feb 19, 2015 8:55 pm

Cytoxan made me sick, so the doc decided against it. I have been on Pomalyst 4 mg and dex for 5 cycles. Results have been good, as my lambda has come down considerably, but the side effects are really rough - mainly fatigue

George

gfcocala
Name: George
Who do you know with myeloma?: self
When were you/they diagnosed?: January 2008
Age at diagnosis: 62


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