[Anne M]

pomalidomide Side effects

by Anne M on Sat Jun 19, 2010 2:28 pm

Hi,

I know that Revlimid is well-known for causing a rash (sometimes moderate, or sometimes quite severe, like in my case). With pomalidomide [Pomalyst], are the researchers seeing this type of reaction (ie rash) in a lot of patients? And more broadly, would you comment on the different overall side effects of pomalidomide as compared to Revlimid?

Thanks very much.

[Dr. Craig Hofmeister]

Re: pomalidomide Side effects

by Dr. Craig Hofmeister on Tue Sep 07, 2010 5:28 pm

I would say that the incidence of rash was the same or a little bit less than Revlimid based on our experience with the pomalidomide (CC-4047) phase II trial in relapsed and refractory myeloma patients. The remaining side effects closely mirror Revlimid -- fatigue, nausea/diarrhea, rash, count suppression, muscle cramps -- although seem less intense.

[eun]

Re: pomalidomide Side effects

by eun on Thu Aug 02, 2012 11:50 am

I thought I was crazy but I was up half the night scratching my scalp. Thanks for reassuring me.

[escapes]

Re: pomalidomide Side effects

by escapes on Thu Aug 09, 2012 11:02 am

I just began in a clinical trial at Emory

A Phase 1, Multicenter, Open-Label, Dose-escalation Study to Determine the Maximum Tolerated Dose for the Combination of pomalidomide, Bortezomib and Low-Dose Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

CC-4047-MM-005

http://clinicaltrials.gov/ct2/show/NCT01497093

Will try to post side effects, after 2 years on RVD hoping for some lesser side effects

Steve