Hi - today I took my mother to an hemo-oncologist because her WBC is 32,000 and she is being assessed for Chronic Lymphocyctic Leukemia (CLL). During the exam, he asked if any family members have a blood disorder/cancer. I told him I have Ig MGUS chromosome 7 with a 1.5 spike that has stayed the same for 10 months. He said usually the MGUS trisomics transition into multiple myeloma within 7-8 years and hopefully new treatment options will be available at that time. Is this the norm for those with MGUS assoc with chromosome 7? MGUS is the precancerous condition for multiple myeloma and usually has a specific chromosome involved. Do those anomalies (trisomics, translocations, etc) transition at different rates?
Since I have MGUS and it appears my mom will be diagnosed with CLL am I wrong to assume there is some type of genetic issue associated with our plasma cells? Diane
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