Hello again from the UK. Has anyone heard of side effects of Velcade and dex going on for over 8 weeks after treatment stopped. I am still getting nausea, blurred vision and light headedness and it is starting to worry me. All my blood tests are normal.
I would be very grateful for any advice.
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nicholas sutton - Name: nicholas sutton
- Who do you know with myeloma?: myself
- When were you/they diagnosed?: 16/01/2014
- Age at diagnosis: 60
Re: Persisting side effects long after treatment has stopped
Dear Nicholas,
Although in most circumstances side effects related to chemotherapy regimens such as Velcade plus dexamethasone improve after the agents are discontinued, there are situations in which such effects may linger for a longer period of time. An example of this as it relates to Velcade is peripheral neuropathy, which typically improves after Velcade is discontinued but can persist.
The nausea and dizziness you're experiencing could be related to the effect of Velcade on the autonomic nervous system. On the other hand, visual symptoms are not common with Velcade. Prolonged exposure to dexamethasone or other corticosteroids is associated in a relatively small percentage of individuals with the development of cataracts.
Recognizing these possibilities, I suggest you discuss these symptoms with your medical team and explore appropriate diagnostic studies to further evaluate and any necessary interventions that may help.
In the course of evaluation, your medical team will also undoubtedly consider other factors that may be contributing to the symptoms you're experiencing.
Although in most circumstances side effects related to chemotherapy regimens such as Velcade plus dexamethasone improve after the agents are discontinued, there are situations in which such effects may linger for a longer period of time. An example of this as it relates to Velcade is peripheral neuropathy, which typically improves after Velcade is discontinued but can persist.
The nausea and dizziness you're experiencing could be related to the effect of Velcade on the autonomic nervous system. On the other hand, visual symptoms are not common with Velcade. Prolonged exposure to dexamethasone or other corticosteroids is associated in a relatively small percentage of individuals with the development of cataracts.
Recognizing these possibilities, I suggest you discuss these symptoms with your medical team and explore appropriate diagnostic studies to further evaluate and any necessary interventions that may help.
In the course of evaluation, your medical team will also undoubtedly consider other factors that may be contributing to the symptoms you're experiencing.
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Dr. Jacob Laubach - Name: Jacob Laubach, M.D., M.P.P.
Beacon Medical Advisor
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