Hi all,
Does osteoporosis meet the "B" (bone damage) part of the "CRAB" criteria for a multiple myeloma diagnosis, where CRAB stands for
C = elevated Calcium levels in the blood
R = Renal insufficiency (kidney damage)
A = Anemia
B = Bone damage?
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Mojbahar - Name: M
- Who do you know with myeloma?: Self mgus
- When were you/they diagnosed?: Jully 2016
- Age at diagnosis: 48
Re: Osteoporosis and CRAB criteria for multiple myeloma
Hi M,
Osteoporosis OR the presence of lytic lesions used to be the criteria to meet the "B" in the CRAB requirements . However, the latest 2015 IMWG criteria no longer recommends the presence of osteoporosis in the absence of lytic lesions as being sufficient evidence of bone disease (the "B" in CRAB) for the purposes of a symptomatic multiple myeloma diagnosis.
Osteoporosis OR the presence of lytic lesions used to be the criteria to meet the "B" in the CRAB requirements . However, the latest 2015 IMWG criteria no longer recommends the presence of osteoporosis in the absence of lytic lesions as being sufficient evidence of bone disease (the "B" in CRAB) for the purposes of a symptomatic multiple myeloma diagnosis.
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Multibilly - Name: Multibilly
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Smoldering, Nov, 2012
Re: Osteoporosis and CRAB criteria for multiple myeloma
Thank you very much Multibilly.
I had an appointment last Thursday with a myeloma specialist, which went well. He said most probably I don't have multiple myeloma, but if I want to rule it out I must do the bone marrow biopsy. He also ordered a bone density test, which I did it on Friday, and I was told by the radiologist I have osteoporosis and that made me worried. I did the whole body skeleton X-ray and that was clear. He ran lots of blood work and I will see him on Thursday to go over the results, I am very scared of doing the bone marrow biopsy, but most probably I will do it to get it over with.
I appreciate your quick response as usual.
I had an appointment last Thursday with a myeloma specialist, which went well. He said most probably I don't have multiple myeloma, but if I want to rule it out I must do the bone marrow biopsy. He also ordered a bone density test, which I did it on Friday, and I was told by the radiologist I have osteoporosis and that made me worried. I did the whole body skeleton X-ray and that was clear. He ran lots of blood work and I will see him on Thursday to go over the results, I am very scared of doing the bone marrow biopsy, but most probably I will do it to get it over with.
I appreciate your quick response as usual.
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Mojbahar - Name: M
- Who do you know with myeloma?: Self mgus
- When were you/they diagnosed?: Jully 2016
- Age at diagnosis: 48
Re: Osteoporosis and CRAB criteria for multiple myeloma
If the bone marrow biopsy worries you, call in advance to get Ativan (lorazepam) and a narcotic. I have done 6 bone marrow biopsies, both with and without drugs, and I prefer with. Just make sure to get a ride home.
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Arizonan - Name: Arizonan
- Who do you know with myeloma?: Self
- When were you/they diagnosed?: April 2010
- Age at diagnosis: 54
Re: Osteoporosis and CRAB criteria for multiple myeloma
Thanks, Arizonan, very good tip.
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Mojbahar - Name: M
- Who do you know with myeloma?: Self mgus
- When were you/they diagnosed?: Jully 2016
- Age at diagnosis: 48
Re: Osteoporosis and CRAB criteria for multiple myeloma
I did the bone marrow biopsy this morning, and it was much better than what I though it would be. I took your advice, Arizonan, and thank, thanks, thanks. It did help a lot. Just discomfort, not lots of pain.
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Mojbahar - Name: M
- Who do you know with myeloma?: Self mgus
- When were you/they diagnosed?: Jully 2016
- Age at diagnosis: 48
Re: Osteoporosis and CRAB criteria for multiple myeloma
Osteoporosis / osteopenia can come from multiple myeloma. For sure in my case anyway. But I'm still in my 30's, so osteoporosis in a 30-something is pretty rare without a cause like myeloma. I had lytic lesions though. so guess that fits.
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lys2012 - Name: Alyssa
- When were you/they diagnosed?: 2010, Toronto, Canada
- Age at diagnosis: 32
Re: Osteoporosis and CRAB criteria for multiple myeloma
Mojbahar wrote:
My husband just had his bone marrow biopsy two weeks ago and I was allowed to observe. It was a 'bedside' biopsy, which just means the oncologist did the procedure in my husband's hospital room. Before beginning the biopsy, the doc injected an anesthetic all around the site and also injected it inside the tissue that was closer to the bone. The biopsy was taken from the back of the pelvis, about 3 inches away from the spine. First the doc withdrew a sample of the fluid from the bone, and then used another tool to harvest a sample of the bone marrow. My husband was awake and alert for the entire procedure and managed fine. It sounds like a scary procedure, but really isn't. Good luck with your test.
Terry
"I am very scared of doing the bone marrow biopsy, but most probably I will do it to get it over with.
My husband just had his bone marrow biopsy two weeks ago and I was allowed to observe. It was a 'bedside' biopsy, which just means the oncologist did the procedure in my husband's hospital room. Before beginning the biopsy, the doc injected an anesthetic all around the site and also injected it inside the tissue that was closer to the bone. The biopsy was taken from the back of the pelvis, about 3 inches away from the spine. First the doc withdrew a sample of the fluid from the bone, and then used another tool to harvest a sample of the bone marrow. My husband was awake and alert for the entire procedure and managed fine. It sounds like a scary procedure, but really isn't. Good luck with your test.
Terry
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Terry G
8 posts
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