[lucifer]

What is the normal bone marrow plasma cell percentage?

by lucifer on Sun Apr 30, 2017 6:19 am

Hi,

A trace of a tiny IgA lambda paraprotein was found and my haematologist is giving me thorough testing as per my request. I've opted to have a bone marrow biopsy. This will happen on the 8th May.

Quick question regarding the potential results. I've read a lot of posts with people talking about bone marrow biopsies when they have MGUS and a figure of under 5% plasma cells is mentioned.

My question is this: Should there be any plasma cells shown if the person does not have MGUS. To clarify, I'm asking if a bone marrow biopsy is "normal", should any plasma cells be seen?

Hope that makes sense!

Thank you and best wishes,

Lucy

[Multibilly]

Re: What is the normal bone marrow plasma cell percentage?

by Multibilly on Sun Apr 30, 2017 12:36 pm

Lucy,

A person without any sort of monoclonal gammopathy should have a bone marrow plasma cell percentage between 0-5%.

[lucifer]

Re: What is the normal bone marrow plasma cell percentage?

by lucifer on Sun Apr 30, 2017 1:25 pm

Thanks for the reply Multibilly!

[Jack0305]

Re: What is the normal bone marrow plasma cell percentage?

by Jack0305 on Fri May 05, 2017 3:01 am

I think it is 3%.

[CautiouslyOptimistic]

Re: What is the normal bone marrow plasma cell percentage?

by CautiouslyOptimistic on Wed May 17, 2017 1:08 pm

Should it maybe be clarified that a bone marrow biopsy is normal with up to 5% normal plasma cells?

The reason I ask is because my bone marrow biopsy found only 1% plasma cells, but they were all malignant. At least the pathologist report indicated normal plasma cells not identified.

[Multibilly]

Re: What is the normal bone marrow plasma cell percentage?

by Multibilly on Wed May 17, 2017 6:37 pm

Good clarification C.O.

So, a normal bone marrow biopsy would actually be "up to 5% normal plasma cells, with no abnormal plasma cells being detected".