[GrandmaofFour]

Negative M-spike - what does it mean?

by GrandmaofFour on Sun Jan 03, 2016 9:58 am

My hubby has had IgG and IgM multiple myeloma since 2004. He has only one time dropped into the normal range after a lot of chemo! His IgG and IgM numbers hover just outside the normal range. He has not had a stem cell transplant nor has he had any treatment since the end of 2007. His M spike remained normal since then.

However, for the past year, the M-spike has gone into a negative value of 0.6. Shows up RED on his blood work. WHAT does that mean? Is it an indicator that the multiple myeloma is possibly re-awakening? The oncologist has said nothing.

Just wondering! And, thank you very much!

[JimNY]

Re: Negative M-spike - what does it mean?

by JimNY on Sun Jan 03, 2016 10:36 am

Welcome to the forum, Grandma.

You say your husband's M-spike has been normal until recently. Do you mean that it was zero?

Also, you say that your husband's M-spike is now negative 0.6. Are you assuming that it is negative because it is printed in red, or is it actually printed as -0.6 (0.6 with a negative sign in front of it) on your husband's lab results?

[mikeb]

Re: Negative M-spike - what does it mean?

by mikeb on Mon Jan 04, 2016 5:05 pm

Hi GrandmaofFour,

Following up on JimNY's reply, I think your husband's M-spike showed up in red to indicate that it is an abnormal lab result. Normal is 0.0 for the M-spike. There is no such thing as a negative M-spike. That would be an M-dip, instead ofMm-spike.

In all seriousness, though, the M-spike of 0.6 is something worth discussing with your husband's oncologist.

Best wishes to you and your husband.
Mike