[Marti]

Myeloma Genetics

by Marti on Sun Apr 10, 2011 9:02 pm

Ongoing research is investigating whether human leukocyte antigen (HLA)-Cw5 or HLA-Cw2 may play a role in the pathogenesis of multiple myeloma.

I found the statement above on the EMedicineMedscape website in a Myeloma definiton. Is anyone aware of who might be doing the antigen reseach mentioned ? Thanks

[Ricardo]

Re: Myeloma Genetics

by Ricardo on Mon Apr 11, 2011 2:00 am

Hi Marti,

I'm not a biochemist or geneticist, so I can't answer your question with a lot of certainty. However, I think there is lot of research going on related to antigens and myeloma. See, for example, the results of this search at Pubmed.gov,

http://www.ncbi.nlm.nih.gov/pubmed?term=antigen%20myeloma

Specifically regarding HLA-Cw2 and -Cw5, it appears that most of that research was done 10-30 years ago. See these links for some references:

http://www.ncbi.nlm.nih.gov/pubmed?term=cw2%20myeloma
http://www.ncbi.nlm.nih.gov/pubmed?term=cw5%20myeloma

Hope this helps.