Hello all,
My mother already has osteoporosis and a fatty liver, and high blood pressure. She's 59. She's under control having regular blood tests etc and using medicine for these. Well, last year her doctors decided to send her to hematologist since they saw something wrong in her blood.
Here is her recent test results and I am afraid that she has multiple myeloma. I am very sad since evening, crying. Please help me by looking at these results.
BASO% 0.4 (0.3-1.5)
WBC 8.7 (4.0-10.3)
NEU% 56.4 (41.0-73.0)
LYM% 34.6 (19.4-44.9)
MONO% 6.7 (5.1-10.9)
EOS% 1.9 (0.9-6.0)
NEU# 4.9 (2.1-6.1)
LYM# 3 (1.3-3.5)
MONO# 0.6 (0.3-0.9)
EOS# 0.2 (0.0-0.5)
BASO# 0 (0.0-0.2)
RBC 4.68 (4.00-5.77)
HGB 13.5 (12.0-16.0)
HCT 40 (36-46)
MCV 85.5 (80.7-95.5)
MCH 28.9 (27.2-33.5)
MCHC 33.8 (32.7-35.6)
RDW 14.2 (11.8-14.3)
PLT 310 (156-373)
MPV 9.8 (6.9-10.8)
PCT 0.3
BUN 16.3 (8-23)
Creatinin 0.75 (0.66-1.09)
MDRD eGFR 78.8 (>90)
Uric Acid 6 (2.6-6)
AST 19 (0-35)
ALT 22 (0-35)
CK 83 (0-145)
LDH 219 (125-220)
ALP 95 (30-120)
GGT 25 (0-38)
Total Protein 7.86 (6.6-8.3)
Albumin 3.71 (3.5-5.2)
Total Ig E 322 (0-100)
Total Bilirubin 0.65 (0.3-1.2)
Direct Bilirubin 0.14 (0.0-0.2)
Indirect Bilirubin 0.51
Calcium 9.1 (8.8-10.6)
Phosphor, inorganic 2.6 (2.8-4.1)
Sodium 138 (136-145)
Potassium 4.85 (3.5-5.1)
Chloride 102 (98-107)
CRP 13.6 (0.2-5.0)
Globulin 4.15
IgA 439 (70-400)
lgG 2002 (700-1600)
lgM 144 (40-230)
Sed rate 36 (0-20)
Some of her test results haven't been released yet. But I am worried about especially the lg things. Thanks in advance for your help.
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Re: My mother's test results
Hello tonhuger,
The laboratory results you have posted do not confirm (or necessarily suggest) a diagnosis of multiple myeloma. I would want to see the results of her serum protein electrophoresis (SPEP), bone marrow biopsy, and Xrays of all of her major bones. The mild elevation in her IgG is non specific. Please keep us informed at the Beacon as to the final results of her evaluation. Hopefully this will not add up to a diagnosis of multiple myeloma.
The laboratory results you have posted do not confirm (or necessarily suggest) a diagnosis of multiple myeloma. I would want to see the results of her serum protein electrophoresis (SPEP), bone marrow biopsy, and Xrays of all of her major bones. The mild elevation in her IgG is non specific. Please keep us informed at the Beacon as to the final results of her evaluation. Hopefully this will not add up to a diagnosis of multiple myeloma.
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Dr. Edward Libby - Name: Edward Libby, M.D.
Beacon Medical Advisor
Re: My mother's test results
Thanks a lot. She's been seeing the hematologist for a year and they have only asked for blood tests. Her serum protein electrophoresis results haven't come yet. She'll be seeing the doctor in the next month, I don't know if they ask for biopsy or Xrays. I'll keep you posted. Thanks a lot for your help again, Dr. Libby.
Re: My mother's test results
Hello all,
My mother already has osteoporosis and a fatty liver, and high blood pressure. She's 59. She's under control having regular blood tests etc and using medicine for these. Well, last year her doctors decided to send her to hematologist since they saw something wrong in her blood.
Here is her recent test results and I am afraid that she has multiple myeloma. Please help me by looking at these results.... I had posted some of these before but now there are new ones. Thanks in advance.
BASO% 0.4 (0.3-1.5)
WBC 8.7 (4.0-10.3)
NEU% 56.4 (41.0-73.0)
LYM% 34.6 (19.4-44.9)
MONO% 6.7 (5.1-10.9)
EOS% 1.9 (0.9-6.0)
NEU# 4.9 (2.1-6.1)
LYM# 3 (1.3-3.5)
MONO# 0.6 (0.3-0.9)
EOS# 0.2 (0.0-0.5)
BASO# 0 (0.0-0.2)
RBC 4.68 (4.00-5.77)
HGB 13.5 (12.0-16.0)
HCT 40 (36-46)
MCV 85.5 (80.7-95.5)
MCH 28.9 (27.2-33.5)
MCHC 33.8 (32.7-35.6)
RDW 14.2 (11.8-14.3)
PLT 310 (156-373)
MPV 9.8 (6.9-10.8)
PCT 0.3
BUN 16.3 (8-23)
Creatinin 0.75 (0.66-1.09)
MDRD eGFR 78.8 (>90)
Uric Acid 6 (2.6-6)
AST 19 (0-35)
ALT 22 (0-35)
CK 83 (0-145)
LDH 219 (125-220)
ALP 95 (30-120)
GGT 25 (0-38)
Total Protein 7.86 (6.6-8.3)
Albumin 3.71 (3.5-5.2)
Total Ig E 322 (0-100)
Total Bilirubin 0.65 (0.3-1.2)
Direct Bilirubin 0.14 (0.0-0.2)
Indirect Bilirubin 0.51
Calcium 9.1 (8.8-10.6)
Phosphor, inorganic 2.6 (2.8-4.1)
Sodium 138 (136-145)
Potassium 4.85 (3.5-5.1)
Chloride 102 (98-107)
CRP 13.6 (0.2-5.0)
Globulin 4.15
IgA 439 (70-400)
lgG 2002 (700-1600)
lgM 144 (40-230)
Sed rate 36 (0-20)
A/G Ratio 0.8
There is suspicious view in the gamma zone
Albumin% 44.4 (50-65)
Alfa 1% 2 (1-3)
Alfa 2% 13.1 (9.5-14.4)
Beta 1% 7.8 (6.0-9.8)
Beta 2% 6.6 (2.6-5.8)
Gamma% 26.1 (10.7-20.3)
My mother already has osteoporosis and a fatty liver, and high blood pressure. She's 59. She's under control having regular blood tests etc and using medicine for these. Well, last year her doctors decided to send her to hematologist since they saw something wrong in her blood.
Here is her recent test results and I am afraid that she has multiple myeloma. Please help me by looking at these results.... I had posted some of these before but now there are new ones. Thanks in advance.
BASO% 0.4 (0.3-1.5)
WBC 8.7 (4.0-10.3)
NEU% 56.4 (41.0-73.0)
LYM% 34.6 (19.4-44.9)
MONO% 6.7 (5.1-10.9)
EOS% 1.9 (0.9-6.0)
NEU# 4.9 (2.1-6.1)
LYM# 3 (1.3-3.5)
MONO# 0.6 (0.3-0.9)
EOS# 0.2 (0.0-0.5)
BASO# 0 (0.0-0.2)
RBC 4.68 (4.00-5.77)
HGB 13.5 (12.0-16.0)
HCT 40 (36-46)
MCV 85.5 (80.7-95.5)
MCH 28.9 (27.2-33.5)
MCHC 33.8 (32.7-35.6)
RDW 14.2 (11.8-14.3)
PLT 310 (156-373)
MPV 9.8 (6.9-10.8)
PCT 0.3
BUN 16.3 (8-23)
Creatinin 0.75 (0.66-1.09)
MDRD eGFR 78.8 (>90)
Uric Acid 6 (2.6-6)
AST 19 (0-35)
ALT 22 (0-35)
CK 83 (0-145)
LDH 219 (125-220)
ALP 95 (30-120)
GGT 25 (0-38)
Total Protein 7.86 (6.6-8.3)
Albumin 3.71 (3.5-5.2)
Total Ig E 322 (0-100)
Total Bilirubin 0.65 (0.3-1.2)
Direct Bilirubin 0.14 (0.0-0.2)
Indirect Bilirubin 0.51
Calcium 9.1 (8.8-10.6)
Phosphor, inorganic 2.6 (2.8-4.1)
Sodium 138 (136-145)
Potassium 4.85 (3.5-5.1)
Chloride 102 (98-107)
CRP 13.6 (0.2-5.0)
Globulin 4.15
IgA 439 (70-400)
lgG 2002 (700-1600)
lgM 144 (40-230)
Sed rate 36 (0-20)
A/G Ratio 0.8
There is suspicious view in the gamma zone
Albumin% 44.4 (50-65)
Alfa 1% 2 (1-3)
Alfa 2% 13.1 (9.5-14.4)
Beta 1% 7.8 (6.0-9.8)
Beta 2% 6.6 (2.6-5.8)
Gamma% 26.1 (10.7-20.3)
Re: My mother's test results
Would need skeletal survey to know if there are bone lesions. Also need quantification of a monoclonal protein. The elevated IgG and IgA levels are more suggestive of a polyclonal hypergammaglobulinemia. But need to make sure there is not a monoclonal protein.
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Dr. Jason Valent - Name: Jason Valent, M.D.
Beacon Medical Advisor
Re: My mother's test results
Dr. Jason Valent wrote:
> Would need skeletal survey to know if there are bone lesions. Also need
> quantification of a monoclonal protein. The elevated IgG and IgA levels
> are more suggestive of a polyclonal hypergammaglobulinemia. But need to
> make sure there is not a monoclonal protein.
Thanks for your reply... She was told that there is no danger for now, they were just controlling... She's going to be checked again about 3 months later.
> Would need skeletal survey to know if there are bone lesions. Also need
> quantification of a monoclonal protein. The elevated IgG and IgA levels
> are more suggestive of a polyclonal hypergammaglobulinemia. But need to
> make sure there is not a monoclonal protein.
Thanks for your reply... She was told that there is no danger for now, they were just controlling... She's going to be checked again about 3 months later.
Re: My mother's test results
Hello all,
My mother already has osteoporosis and a fatty liver, and high blood pressure. She's 60. She's under control having regular blood tests etc and using medicine for these. And for a while, she has been visiting the hematologist for these routine tests.
Here is her recent test results and I am afraid if these results may mean multiple myeloma. She often says that she has leg and foot pain... I don't know if that can be a symptom. She's also fat and feels the pain more after she moves a lot. Thanks in advance.
BASO% 0.5 (0.3-1.5)
WBC 8.1 (4.0-10.3)
NEU% 58.9 (41.0-73.0)
LYM% 32.4 (19.4-44.9)
MONO% 6.1 (5.1-10.9)
EOS% 2.1 (0.9-6.0)
NEU# 4.8 (2.1-6.1)
LYM# 2.6 (1.3-3.5)
MONO# 0.5 (0.3-0.9)
EOS# 0.2 (0.0-0.5)
BASO# 0 (0.0-0.2)
RBC 4.57 (4.00-5.77)
HGB 13.5 (12.0-16.0)
HCT 38.8 (36-46)
MCV 84.9 (80.7-95.5)
MCH 29.6 (27.2-33.5)
MCHC 34.8 (32.7-35.6)
RDW 13,6 (11.8-14.3)
PLT 298(156-373)
MPV 9.9 (6.9-10.8)
PCT 0.293
BUN 12.4 (8-23)
Creatinin 0.56 (0.66-1.09)
MDRD eGFR 110 (>90)
Uric Acid 6.30 (2.6-6)
AST 20 (0-35)
ALT 21 (0-35)
LDH 164 (125-220)
ALP 117 (30-120)
GGT 30 (0-38)
Total Protein 8.05 (6.6-8.3)
Albumin 4.23 (3.5-5.2)
Calcium 9.41 (8.8-10.6)
Sodium 137 (136-145)
Potassium 4.66 (3.5-5.1)
Chloride 103 (98-107)
CRP 14.2 (0.2-5.0)
Globulin 3.82
IgA 471.8 (70-400)
lgG 1851.6 (700-1600)
lgM 148.4 (40-230)
Sed rate 62 (0-20)
Free Lambda Light Chain 47 (8.3-27)
Free Kappa Light Chain 29.30 (6.7-22.4)
In her SPEP, it says that there is no monoclonal gammopathy but there is a slightly suspicious view on lgG. And I have attached the photo of her SPEP.
Thanks in advance.
My mother already has osteoporosis and a fatty liver, and high blood pressure. She's 60. She's under control having regular blood tests etc and using medicine for these. And for a while, she has been visiting the hematologist for these routine tests.
Here is her recent test results and I am afraid if these results may mean multiple myeloma. She often says that she has leg and foot pain... I don't know if that can be a symptom. She's also fat and feels the pain more after she moves a lot. Thanks in advance.
BASO% 0.5 (0.3-1.5)
WBC 8.1 (4.0-10.3)
NEU% 58.9 (41.0-73.0)
LYM% 32.4 (19.4-44.9)
MONO% 6.1 (5.1-10.9)
EOS% 2.1 (0.9-6.0)
NEU# 4.8 (2.1-6.1)
LYM# 2.6 (1.3-3.5)
MONO# 0.5 (0.3-0.9)
EOS# 0.2 (0.0-0.5)
BASO# 0 (0.0-0.2)
RBC 4.57 (4.00-5.77)
HGB 13.5 (12.0-16.0)
HCT 38.8 (36-46)
MCV 84.9 (80.7-95.5)
MCH 29.6 (27.2-33.5)
MCHC 34.8 (32.7-35.6)
RDW 13,6 (11.8-14.3)
PLT 298(156-373)
MPV 9.9 (6.9-10.8)
PCT 0.293
BUN 12.4 (8-23)
Creatinin 0.56 (0.66-1.09)
MDRD eGFR 110 (>90)
Uric Acid 6.30 (2.6-6)
AST 20 (0-35)
ALT 21 (0-35)
LDH 164 (125-220)
ALP 117 (30-120)
GGT 30 (0-38)
Total Protein 8.05 (6.6-8.3)
Albumin 4.23 (3.5-5.2)
Calcium 9.41 (8.8-10.6)
Sodium 137 (136-145)
Potassium 4.66 (3.5-5.1)
Chloride 103 (98-107)
CRP 14.2 (0.2-5.0)
Globulin 3.82
IgA 471.8 (70-400)
lgG 1851.6 (700-1600)
lgM 148.4 (40-230)
Sed rate 62 (0-20)
Free Lambda Light Chain 47 (8.3-27)
Free Kappa Light Chain 29.30 (6.7-22.4)
In her SPEP, it says that there is no monoclonal gammopathy but there is a slightly suspicious view on lgG. And I have attached the photo of her SPEP.
Thanks in advance.
- Attachments
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Re: My mother's test results
Dear tonhuger,
Thanks for the update.
Has your mother had a bone marrow biopsy or x-ray of her bones. A bone marrow biopsy would be helpful.
Myeloma typically does not affect small bones of the feet, but rather long bones. That's why x-rays would be useful.
Also, the elevated IgA, IgG, free kappa and free lambda light chains suggest a polyclonal increase, suggestive NOT of myeloma, but rather an inflammatory or infectious process.
Thanks for the update.
Has your mother had a bone marrow biopsy or x-ray of her bones. A bone marrow biopsy would be helpful.
Myeloma typically does not affect small bones of the feet, but rather long bones. That's why x-rays would be useful.
Also, the elevated IgA, IgG, free kappa and free lambda light chains suggest a polyclonal increase, suggestive NOT of myeloma, but rather an inflammatory or infectious process.
-
Dr. Jatin Shah - Name: Jatin Shah, M.D.
Beacon Medical Advisor
Re: My mother's test results
Thank you very much for the answer.
She hasn't had a bone marrow biopsy but recently she has had a bone densitometry and it came out fine: she has osteoporosis in her hip bone and it is the same as it was before, they said. There is no negative progression.
What kind of other diseases or problems can she have with these test results? Should we be worried?
She hasn't had a bone marrow biopsy but recently she has had a bone densitometry and it came out fine: she has osteoporosis in her hip bone and it is the same as it was before, they said. There is no negative progression.
What kind of other diseases or problems can she have with these test results? Should we be worried?
Re: My mother's test results
Hello,
My mother already has osteoporosis, a fatty liver, Vitamin D deficiency and high blood pressure. She's 62 and over weighted. She's under control having regular blood tests etc and using medicine for these, under the controls of endocrinology and gastroenterology. She says she sometimes has leg pains due to tiredness. Here is her recent test results:
BASO% 0.4 (0.3-1.5)
WBC 9.4 (4.0-10.3)
NEU% 62.7 (41.0-73.0)
LYM% 28.8 (19.4-44.9)
MONO% 5.1 (5.1-10.9)
EOS% 3 (0.9-6.0)
NEU# 5.9 (2.1-6.1)
LYM# 2.7 (1.3-3.5)
MONO# 0.5 (0.3-0.9)
EOS# 0.3 (0.0-0.5)
BASO# 0 (0.0-0.2)
RBC 4.46 (4.00-5.77)
HGB 12.7 (12.0-16.0)
HCT 37.4 (36-46)
MCV 83.8 (80.7-95.5)
MCH 28.5 (27.2-33.5)
MCHC 34 (32.7-35.6)
RDW 14.3 (11.8-14.3)
PLT 248 (156-373)
MPV 10.6 (6.9-10.8)
PCT 0.262
Estimated Sedimantation Rate 35 (0-20)
Glucose 92 (70-100)
BUN 21 (8-23)
Creatinin 0.53 (0.51-0.95)
MDRD eGFR 101 (>90)
Uric Acid 7.26 (2.6-6)
AST 22 (0-35)
ALT 28 (0-35)
LDH 179 (125-220)
ALP 93 (30-120)
GGT 39 (0-38)
Total Protein 7.36 (6.6-8.3)
Albumin 3.59 (3.5-5.2)
Globulin 3.77
Total Bilirubin 0.48 (0.3-1.2)
Direct Bilirubin 0.11 (0.0-0.2)
Indirect Bilirubin 0.37
Calcium 8.88 (8.8-10.6)
Phosphor, inorganic 4.10 (2.8-4.1)
Sodium 139 (136-145)
Potassium 5.02 (3.5-5.1)
Chloride 103 (98-107),
CRP 11.5 (0.2-5)
IgA 389.43 (84,5-499)
lgG 1771.02 (610-1616)
lgM 125.95 (35-242)
Free Kappa Light Chain 41.5207 (3.3-19.4)
Free Lambda Light Chain 18.8296 (5.71-26.3)
Kappa/Lambda Ratio 2.205 (0.26-165)
SPEP:
Albumin% 46.7 (52-65.1)
Alfa 1% 2.2 (1-3)
Alfa 2% 12.5 (9.5-14.4)
Beta 1% 9 (6-9.8)
Beta 2% 9.2 (2.6-5.8)
Gamma% 20.4 (10.7-20.3)
A/G Ratio 0.88
It says that there is no monoclonal gammopathy but a suspicious view on lgG. I have attached the image. I am afraid that she might have multiple myeloma, the kappa/lambda ratio is high.
I don't understand. Is she at risk?
Thanks.
My mother already has osteoporosis, a fatty liver, Vitamin D deficiency and high blood pressure. She's 62 and over weighted. She's under control having regular blood tests etc and using medicine for these, under the controls of endocrinology and gastroenterology. She says she sometimes has leg pains due to tiredness. Here is her recent test results:
BASO% 0.4 (0.3-1.5)
WBC 9.4 (4.0-10.3)
NEU% 62.7 (41.0-73.0)
LYM% 28.8 (19.4-44.9)
MONO% 5.1 (5.1-10.9)
EOS% 3 (0.9-6.0)
NEU# 5.9 (2.1-6.1)
LYM# 2.7 (1.3-3.5)
MONO# 0.5 (0.3-0.9)
EOS# 0.3 (0.0-0.5)
BASO# 0 (0.0-0.2)
RBC 4.46 (4.00-5.77)
HGB 12.7 (12.0-16.0)
HCT 37.4 (36-46)
MCV 83.8 (80.7-95.5)
MCH 28.5 (27.2-33.5)
MCHC 34 (32.7-35.6)
RDW 14.3 (11.8-14.3)
PLT 248 (156-373)
MPV 10.6 (6.9-10.8)
PCT 0.262
Estimated Sedimantation Rate 35 (0-20)
Glucose 92 (70-100)
BUN 21 (8-23)
Creatinin 0.53 (0.51-0.95)
MDRD eGFR 101 (>90)
Uric Acid 7.26 (2.6-6)
AST 22 (0-35)
ALT 28 (0-35)
LDH 179 (125-220)
ALP 93 (30-120)
GGT 39 (0-38)
Total Protein 7.36 (6.6-8.3)
Albumin 3.59 (3.5-5.2)
Globulin 3.77
Total Bilirubin 0.48 (0.3-1.2)
Direct Bilirubin 0.11 (0.0-0.2)
Indirect Bilirubin 0.37
Calcium 8.88 (8.8-10.6)
Phosphor, inorganic 4.10 (2.8-4.1)
Sodium 139 (136-145)
Potassium 5.02 (3.5-5.1)
Chloride 103 (98-107),
CRP 11.5 (0.2-5)
IgA 389.43 (84,5-499)
lgG 1771.02 (610-1616)
lgM 125.95 (35-242)
Free Kappa Light Chain 41.5207 (3.3-19.4)
Free Lambda Light Chain 18.8296 (5.71-26.3)
Kappa/Lambda Ratio 2.205 (0.26-165)
SPEP:
Albumin% 46.7 (52-65.1)
Alfa 1% 2.2 (1-3)
Alfa 2% 12.5 (9.5-14.4)
Beta 1% 9 (6-9.8)
Beta 2% 9.2 (2.6-5.8)
Gamma% 20.4 (10.7-20.3)
A/G Ratio 0.88
It says that there is no monoclonal gammopathy but a suspicious view on lgG. I have attached the image. I am afraid that she might have multiple myeloma, the kappa/lambda ratio is high.
I don't understand. Is she at risk?
Thanks.
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