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General questions and discussion about multiple myeloma (i.e., symptoms, lab results, news, etc.) If unsure where to post, use this discussion area.

Multiple myeloma & risk of other cancers

by Ginny on Wed Apr 08, 2015 8:02 pm

Hello,

I am wondering about others' experience with other cancers in addition to myeloma.

I notice in this thread that a few people said that they had previously been treated for breast cancer, but I cannot find anything else talking about this issue (aside from the cancers known to be caused by chemo, such as ALL).

Does anyone know if other solid tumor cancers are in any way caused or influenced by myeloma or its treatment? Or are myeloma patients simply at the same risk as the rest of the population for lung, colon, breast, etc. cancers?

Ginny D

Ginny
Name: Ginny
Who do you know with myeloma?: self and four friends
When were you/they diagnosed?: October, 2012
Age at diagnosis: 62

Re: Multiple myeloma & risk of other cancers

by Dr. Adam Cohen on Sun Apr 12, 2015 4:50 pm

Several studies have demonstrated that patients with myeloma or even MGUS have a higher baseline risk of developing bone marrow cancers such as myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), and that this risk may be increased further by treatment with melphalan and, in some settings, Revlimid (lenalidomide) maintenance.

The data about solid tumors in myeloma patients is less well-established, though studies do suggest a slightly higher incidence of common solid tumors like prostate or breast cancer. I'm not aware of convincing data that particular myeloma treatments impact this risk.

Myeloma patients should undergo standard age-appropriate cancer screenings (e.g. mam­mo­grams, colonoscopy, etc.), as recommended by their physicians.

Dr. Adam Cohen
Name: Adam D. Cohen, M.D.
Beacon Medical Advisor

Re: Multiple myeloma & risk of other cancers

by Ginny on Tue Apr 14, 2015 2:24 pm

Thanks, Dr. Cohen!

Ginny
Name: Ginny
Who do you know with myeloma?: self and four friends
When were you/they diagnosed?: October, 2012
Age at diagnosis: 62

Re: Multiple myeloma & risk of other cancers

by Nipon Ginko on Wed Apr 15, 2015 9:05 am

I came down with multiple myeloma in 2004 and then about 2.5 years ago came down with prostate cancer. I was operated on and my PSA reading dropped from 10 to 0.005. Things went well till about 6 months ago, when my PSA reading started going up again, and it reached 7. I was put on a series of shots that I get every 4 months. Seems to be working so far, as the PSA reading currently is below 1.

Nipon Ginko
Name: Nipon Ginko
Who do you know with myeloma?: ME
When were you/they diagnosed?: 2004
Age at diagnosis: 66

Re: Multiple myeloma & risk of other cancers

by FEDUP331 on Tue Apr 21, 2015 12:00 pm

I got stomach cancer after stem cell transplant, either from chemo given for transplant or from Protonix (pantoprazole) (they had me on for 3 years). Supposed to be a 6 weeks study.

Madison

FEDUP331

Re: Multiple myeloma & risk of other cancers

by torimooney on Tue Apr 21, 2015 10:38 pm

My multiple myeloma specialist says he sees a link with melanoma and multiple myeloma. I fol­lowed his advice and had a screening by a dermatologist and he found a melanoma. Fortunately, it was early stage.

My dermatologist says cancer suppresses the immune system and therefore we are more likely to develop secondary cancers.

torimooney
Name: tori
Who do you know with myeloma?: myself
When were you/they diagnosed?: apr 2012
Age at diagnosis: 64


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