[Rockman29697]

Multiple myeloma and the heart

by Rockman29697 on Wed Feb 01, 2017 9:17 am

I have a pacemaker (not one that can get your heart going again) and therefore have a couple of heart-related questions:

Does radiation harm the pacemaker and or the leads? Also will the myeloma attack the heart? Does taking Darzalex and Pomalyst have any effects on the heart?

I have asked these questions before; the only one concerned is my heart doctor.

[Multibilly]

Re: Multiple myeloma and the heart

by Multibilly on Wed Feb 01, 2017 3:42 pm

You should read the professional dispensing information regarding Pomalyst. It can indeed potentially impact the heart.

https://www.drugs.com/pro/pomalyst.html

Are you taking a low-dose aspirin or another drug to protect against a potential thrombosis?

To my knowledge, multiple myeloma itself doesn't directly impact heart function unless you have developed hyperviscosity syndrome (thick blood) or you've developed a case of extramedullary (outside the bone in your soft tissue) tumors that directly involves the heart (very rare). However, a variety of multiple myeloma drugs do warrant caution when it comes to potential cardiac issues.

[mrswrench]

Re: Multiple myeloma and the heart

by mrswrench on Wed Feb 01, 2017 5:06 pm

I believe myeloma can affect the heart in other conditions such as light chains depositing in organs including the heart, and some individuals have amyloidosis along with myeloma. I think those instances are rare but possibilities. Your oncologist would probably check this out if there were indications to do so.

As you said, you've asked questions before, and no one seems concerned. There are probably no indications that point to worry in that direction. Hope everything goes well for you.