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MRI says "mild marrow inhomogeneity"?

by cindylouise on Sat Sep 05, 2015 8:50 am

Hi, so I haven't been here in a while, but have a question about my husband's recent MRI of his spine and pelvis. It says mild marrow inhomogeneity in the pelvis may represent mild diffuse myelomatous disease.

Not really sure what this means, and of course these results became available after office hours Friday. Any insight is appreciated.

cindylouise

Re: MRI says "mild marrow inhomogeneity"?

by cindylouise on Sun Sep 06, 2015 6:22 pm

I know this is pretty vague. MRI was obtained during a routine 3 month check up, due to increased low back pain. I think when you are going in to a long weekend, the only results you are hoping for are those that say, clearly, that all is good. Maybe that's what this says. I am currently just mildly concerned.

cindylouise

Re: MRI says "mild marrow inhomogeneity"?

by JimNY on Sun Sep 06, 2015 8:17 pm

Hi Cindy,

Nice to see you back here again.

Does your husband get an MRI of this particular area on a regular basis? If so, is the result / interpretation this time any different than it's been in the past?

JimNY

Re: MRI says "mild marrow inhomogeneity"?

by cindylouise on Sun Sep 06, 2015 9:22 pm

Thank you, and no, he's never had an MRI on his spine or pelvis before. The spinal MRI seems fine.

I want this to be nothing, although nothing just hasn't been in the cards for us the last 4 years. So not good at the waiting game.

cindylouise

Re: MRI says "mild marrow inhomogeneity"?

by CindyBrown on Mon Sep 07, 2015 10:03 am

I had two spinal MRIs which led to my diagnosis and then two during my transplants. The trans­plant MRIs are called "bone marrow/ whole body's" MRIs. The myeloma measurement of activity in all 4 studies was a measuring of marrow signal intensity. I have not heard your term before.

Cindy

CindyBrown
Name: Cindy Brown
Who do you know with myeloma?: Myself
When were you/they diagnosed?: 4/26/14
Age at diagnosis: 48

Re: MRI says "mild marrow inhomogeneity"?

by JimNY on Tue Sep 08, 2015 5:22 pm

Hello again CindyLouise,

Too bad there isn't a previous MRI to compare the latest one to. I would think it would make it easier to figure out whether the "mild diffuse myelomatous disease" is something new, or a remnant of disease that your husband previously had in that area.

Basically, I think there are two possibilities. The first is that is that this is a new area of myeloma activity, and the second is that it's a holdover from previous activity. I really don't know whether the second is really a possibility. But if it is, they may decide to do a PET/CT, or maybe biopsy the area, to investigate it further.

Has there been any change in your husband's M-spike or free light chain levels recently that might suggest that the spot on the MRI is new myeloma activity? If his labs haven't really changed, I would take that as a good sign.

I hope it turns out to be nothing to be worried about. Good luck!

JimNY


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