I received 2 cycles of chemotherpy i went in sCR and i decided not to proceed to a SCT. It was my personal decision to stay out of treatment for 3 months and then make the necessary testings and decide how to continue. I received today the results of the testing. Everything was great except that the the multi parameter flow cytometry has shown 0.05% of cancer cells. How serious is that? Do i have a chance of eliminating them if i proceed to a SCT?
Thank you all
Donna
Forums
4 posts
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Re: Minimal residual disease
HI Donna,
If you have no cells by flow cytometry it is said you are in Immunophenotypic remission. This articles discusses this. Patients with sCR and IR have longer remissions. It is really your choice. It seems like you are responding well to chemo. Have they discussed more cycles of your induction to possibly get IR? Patients get IR's without SCT.
"Conversely, patients with persistent MM-PCs by MFC who were immunofixation negative showed a tendency for early reappearance of the M-component. These latter patients correspond to those previously referred to as early responders but early relapsing,41 and may illustrate the value of MFC analysis in identifying patients who will be unable to sustain their CR status, which is associated with a poor outcome.41 Taken together, these results highlight the need for more sensitive techniques to assess patient response."
Check out Figure 3.
http://jco.ascopubs.org/content/29/12/1627.full
Mark
If you have no cells by flow cytometry it is said you are in Immunophenotypic remission. This articles discusses this. Patients with sCR and IR have longer remissions. It is really your choice. It seems like you are responding well to chemo. Have they discussed more cycles of your induction to possibly get IR? Patients get IR's without SCT.
"Conversely, patients with persistent MM-PCs by MFC who were immunofixation negative showed a tendency for early reappearance of the M-component. These latter patients correspond to those previously referred to as early responders but early relapsing,41 and may illustrate the value of MFC analysis in identifying patients who will be unable to sustain their CR status, which is associated with a poor outcome.41 Taken together, these results highlight the need for more sensitive techniques to assess patient response."
Check out Figure 3.
http://jco.ascopubs.org/content/29/12/1627.full
Mark
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Mark
Re: Minimal residual disease
Thank you Mark. Thats what i am afraid of. Previous time MFC had shown 0% of cancer cells
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Anonymous
4 posts
• Page 1 of 1