[RWhiles33]

MGUS or multiple myeloma?

by RWhiles33 on Tue Jan 09, 2018 3:10 pm

Hope it's okay to run these figures in regards to my MGUS / multiple myeloma.

IgG is 2585 (700-1600)
IgA 232 (61-437)
IgM 50 (15-143).

Red Blood Cells 4.26 (4.40-5.80)
Hemoglobin 13.8 (13.8-17.2)
Hematocrit 41 (41.0-50.0)
White Blood Cells 4.4 (3.8-10.8)
Kappa Light Chain Free 29.7 (3.3-19.4)
Kappa/Lambda Ratio 2.52 (0.26-1.65).

Under test interpretation it says:

"In serum, the Kappa/Lambda ratio of whole immunoglobulin molecules is 2:1, whereas the Kappa/Lambda ratio of free light chain is 1:1.5".

I don't understand this which ratio is the most relevant.

Glucose 94
BUN 25 (3-29)
BUN/Creatinine Ratio 23 (7-25)
Total Protein 8.1 (6.0-8.3)

24-Hour Urine test says:

"No monoclonal Proteins Identified."

Bone Marrow test states:

"Demonstrates involved kappa clonal plasma cells in the amount of 5%."

My current symptoms include somewhat low energy levels, numb feet (peripheral neuropathy), rather constant low level headaches, and shrinking muscle mass in shoulders (bone loss?). I am currently exercising 4-5 times per week using weights and elliptical machine while limiting exercise time to 30 minutes per workout. I am 84 years old.

I am still not clear if the above details would indicate what my "M-spike" is. I don't see any mention of "M-spike."

Are the above symptoms suggestive of multiple myeloma, or can they still be classified as MGUS?

I will be meeting with my hematologist in nine days. I'm trying to understand all of this.

Thank you.

Robert

[willow75]

Re: MGUS or multiple myeloma?

by willow75 on Tue Jan 09, 2018 5:51 pm

Hi Robert,

Do you know if all of your results have come back? I don't see a serum protein electrophoresis (SPEP) test result, which I think is where an M-spike or monoclonal protein level would show up. When I had all my testing done, that was the one that took the longest to come back (about a week), so you might still be waiting for it. I think your doctor will want that number as part of his interpretation.

I'm new here, too, so I can't offer too much more. The bone marrow biopsy result of 5% clonal cells fits within MGUS criteria, but I think you need more data.

-W