[SteveS]

Implications of MGUS & difference from other diagnoses?

by SteveS on Tue Sep 29, 2015 1:36 pm

Hi,

I'm currently undergoing tests after the haematologist found abnormal paraprotein levels in my blood whilst testing following anaemia. I've been told that this could be for a number of reasons and that, as I have a history of B12 deficiency, this is likely to be nothing to worry about. I also suffer from depression (which may, or may not, be linked to B12 deficiency).

I am worried about the outcome of the further tests (CT) and the implications of MGUS and the differences between this and asymptomatic myeloma. Looking at other posts on here, it looks like in the US a lot more data is shared, or maybe I just need to ask for it, but equally researching matters on your own can prove dangerous, I'm probably far more worried than I need be.

Thanks

[Multibilly]

Re: Implications of MGUS & difference from other diagnoses?

by Multibilly on Wed Sep 30, 2015 9:14 am

Hi Steve,

Welcome to the forum.

It seems like you are asking what the difference is between MGUS and other monoclonal gammopathies such as as smoldering (asymptomatic) myeloma and symptomatic multiple myeloma. I would suggest reading this handbook as a starting point.

Keep in mind the point that the handbook makes about the risk of progression from MGUS to symptomatic multiple myeloma only being about 1%/year. Most folks with MGUS are never any the worse for it.