Nancy: I wish your friend a positive resolution of this difficult dilemma. I hope whatever course of action is chosen will work. This is indeed a rare thing to have and therefore more difficult to make treatment decisions about. Sending best wishes.
Blueblood: Both of my sister's plasmacytoma relapses were at the background of seemingly complete multiple myeloma remission. However, a new M-spike followed soon after the first plasmacytoma relapse. This time, an M-spike has not yet shown (this one is post transplant). To answer your questions: NO, we do not believe my sister's myeloma is stable. In fact, we'd prefer the multiple myeloma to relapse without extramedullary plasmacytomas, as we have grown to believe that those are a sign of a particularly aggressive disease with a poor prognosis. Though, luckily, in some cases people do well against all odds.
Forums
-
Gala - Name: Gala
- Who do you know with myeloma?: sister, LgA-k
- When were you/they diagnosed?: December 2015
- Age at diagnosis: 48
Re: Mastectomy for plasmacytomas in the breast
Gala,
My friend told me this week that the myeloma that was identified in the plasmacytomas was different from the myeloma that was identified in her bone marrow. So, the initial myeloma responds well to the conventional treatment that she has received, but the plasmacytoma myeloma didn't.
She is recovering well from the mastectomy and reconstruction that was done because so much tissue had to be removed from the breast area. Slowly she is beginning to gain a little optimism. She has asked every myeloma specialist that she comes across about what they know about plasmacytomas in the breast area and possible treatment when they don't respond to drugs. There is almost nothing available in the literature about such a case. So far the oncologists that she has spoken too have supported the decisions that her specialist has made.
Hoping your sister begins to respond to treatment and starts to feel some better,
Nancy in Phila
My friend told me this week that the myeloma that was identified in the plasmacytomas was different from the myeloma that was identified in her bone marrow. So, the initial myeloma responds well to the conventional treatment that she has received, but the plasmacytoma myeloma didn't.
She is recovering well from the mastectomy and reconstruction that was done because so much tissue had to be removed from the breast area. Slowly she is beginning to gain a little optimism. She has asked every myeloma specialist that she comes across about what they know about plasmacytomas in the breast area and possible treatment when they don't respond to drugs. There is almost nothing available in the literature about such a case. So far the oncologists that she has spoken too have supported the decisions that her specialist has made.
Hoping your sister begins to respond to treatment and starts to feel some better,
Nancy in Phila
-
NStewart - Name: Nancy Stewart
- Who do you know with myeloma?: self
- When were you/they diagnosed?: 3/08
- Age at diagnosis: 60
Re: Mastectomy for plasmacytomas in the breast
Hi Nancy,
I am glad your friend has had treatment for her plasmacytomas. It sounds like the decision was made after a careful consideration and that she is in good hands. I wish her all the very best.
It is interesting what you write about two different myelomas in one person. It actually could be my sister's case also, though it has never been mentioned. At the moment her blood tests are good, but the plasmacytoma biopsy is showing very fast dividing cells that are multiplying aggressively. I agree that there is not much in literature.
My sister has almost completed her radiation treatment and the tumor is responding. She is due to start systemic treatment with Velcade, Revlimid, and dexamethasone after she finishes radiation next week.
Thank you for your good wishes. I'll keep you posted.
I am glad your friend has had treatment for her plasmacytomas. It sounds like the decision was made after a careful consideration and that she is in good hands. I wish her all the very best.
It is interesting what you write about two different myelomas in one person. It actually could be my sister's case also, though it has never been mentioned. At the moment her blood tests are good, but the plasmacytoma biopsy is showing very fast dividing cells that are multiplying aggressively. I agree that there is not much in literature.
My sister has almost completed her radiation treatment and the tumor is responding. She is due to start systemic treatment with Velcade, Revlimid, and dexamethasone after she finishes radiation next week.
Thank you for your good wishes. I'll keep you posted.
-
Gala - Name: Gala
- Who do you know with myeloma?: sister, LgA-k
- When were you/they diagnosed?: December 2015
- Age at diagnosis: 48
13 posts
• Page 2 of 2 • 1, 2
Return to Treatments & Side Effects