Hello,
I received my results today.
My M-spike (Electro G globulines pic) was 14.9 g/L (1.49 g/dL) in May and is 18.1 g/L (1.81 g/dL) now. It's the highest I ever had.
But the hematologist took only care of Electro G globulins, which are 20.8 g / L (normal: 6.8 - 14.9), and was 17.7 g / L in May. He considers as moderate the progress, and other analyses are correct (no anemia, etc.). Proteinuria was measured at 0.5 g / L of urine sample.
I saw this hematologist 1/4 hour consultation. I did not succeeded to ask him if I was in MGUS, or smoldering (I'm gammopathy stage 1), and if I could stay like this all my life or need treatment soon.
This is a very good specialist but he spent the consultation to criticize me because I had taken the advice of a nephrologist for proteinuria. He says it is unnecessary expense for social security (in France, I pay nothing, neither doctor nor analysis for gammopathy).
Nevertheless, he was reassuring.
But I still have a blood test to do in 2 months, and closer analysis, it is not going in the direction to reassure me.
What about this M spike that always rises?
Jacqueline
IgG kappa
Forums
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Re: M-spike increasing - what does it mean?
Hi Jacqueline,
You are like my wife with her M-spike level and being IgG kappa. Sometimes the M-spike numbers stop rising, and even decline slightly, for periods of time. Generally, you have a 1% chance each year to develop myeloma, or a 20% chance in 20 years of progressing from MGUS (M-spike) to myeloma. However, there are many other factors that change this general statement.
The simple definition of "smoldering" myeloma is an M-spike greater than 3.0 g/dL and/or 10 to 60 percent bone marrow clonal plasma cells without bone lesions, anemia, or kidney problems. If you reach smoldering, some patients do not require immediate treatment depending on their risk for progression. Treatment in this field of hematology medicine is advancing and has improved results for patients.
My advice is to obtain copies of your blood tests every two months and monitor the changes in the abnormal blood test ranges. Talk with your physician about these changes while reading as much as you can about smoldering myeloma and multiple myeloma.
You are like my wife with her M-spike level and being IgG kappa. Sometimes the M-spike numbers stop rising, and even decline slightly, for periods of time. Generally, you have a 1% chance each year to develop myeloma, or a 20% chance in 20 years of progressing from MGUS (M-spike) to myeloma. However, there are many other factors that change this general statement.
The simple definition of "smoldering" myeloma is an M-spike greater than 3.0 g/dL and/or 10 to 60 percent bone marrow clonal plasma cells without bone lesions, anemia, or kidney problems. If you reach smoldering, some patients do not require immediate treatment depending on their risk for progression. Treatment in this field of hematology medicine is advancing and has improved results for patients.
My advice is to obtain copies of your blood tests every two months and monitor the changes in the abnormal blood test ranges. Talk with your physician about these changes while reading as much as you can about smoldering myeloma and multiple myeloma.
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LuvHiking - Name: LuvHiking
- Who do you know with myeloma?: Wife
- When were you/they diagnosed?: Waiting for diagnosis
- Age at diagnosis: 50
2 posts
• Page 1 of 1