Hi,
I just got my lab results back and my M-Spike went from 2.34 g/dL down to 1.71 g/dL which I am happy about. But my IgG went from 2990 mg/dL up to 3080 mg/dL. And every time that goes up my IgM goes down. It went from 39 mg/dL down to 35 mg/dL.
Is either the M-Spike or the IgG level more indicative of something than the other one ? I had a BMB about 10 months ago and my protein level was at 5%. Bone scan at the same time was negative.
Any input would be much appreciated.
Mike
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MJW2208 - Name: Mike
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: MGUS 5/2014, SMM 5/2017
- Age at diagnosis: 55
Re: M-spike going down but IgG going up
Hello Mike,
I am not a doctor, just someone who has MGUS as well. Are you seeing a myeloma specialist? And what did your doctor say about these results?
The little calculation I have read about on these boards is that if you take your m-spike x10 then subtract from the involved immunoglobulin total, that gives you an approximation of what your normal (non-monoclonal / non-myeloma) immunoglobulin actually is. So 1.71 x10 = @ 1,710 - 3,080 = 1,370, which probably falls in the "normal" range (I believe it's between 700-1,600).
The immunoglobulin A is slightly lower than normal at 35 - 39.
The important thing isn't usually one lab result, but rather tracking to see if there are significant changes over time - a trend.
When they did your BMB, were they able to analyze to see if there were any chromosomal abnormalities or see what percentage of cells were aberrant?
I haven't really provided you with "answers," but what I have learned is that it is very important to look at the bigger picture. I also believe strongly that having a specialist is imperative.
You've come to a good place though! The Myeloma Beacon is very informative!
Toni
I am not a doctor, just someone who has MGUS as well. Are you seeing a myeloma specialist? And what did your doctor say about these results?
The little calculation I have read about on these boards is that if you take your m-spike x10 then subtract from the involved immunoglobulin total, that gives you an approximation of what your normal (non-monoclonal / non-myeloma) immunoglobulin actually is. So 1.71 x10 = @ 1,710 - 3,080 = 1,370, which probably falls in the "normal" range (I believe it's between 700-1,600).
The immunoglobulin A is slightly lower than normal at 35 - 39.
The important thing isn't usually one lab result, but rather tracking to see if there are significant changes over time - a trend.
When they did your BMB, were they able to analyze to see if there were any chromosomal abnormalities or see what percentage of cells were aberrant?
I haven't really provided you with "answers," but what I have learned is that it is very important to look at the bigger picture. I also believe strongly that having a specialist is imperative.
You've come to a good place though! The Myeloma Beacon is very informative!
Toni
-
Toni - Name: Toni
- Who do you know with myeloma?: self - MGUS
- When were you/they diagnosed?: April 2014
- Age at diagnosis: 51
2 posts
• Page 1 of 1