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Light chain escape vs. light chain deposition disease
Are light chain escape and light chain deposition disease the same thing?
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JBritt - Name: Jewell
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: October 2015
- Age at diagnosis: 64
Re: Light chain escape vs. light chain deposition disease
Hi Jewell,
No.
Light chain escape is by definition a phenomenon that can occur post-treatment, where the body secretes monoclonal light chains at a rate greater than the corresponding intact monoclonal immunoglobulin (i.e. M-spike) rate. It can occur in myeloma patients.
Light chain deposition disease (LCDD) is actually a disease (as opposed to a phenomenon) that is distinct from myeloma (but often is accompanied by a myeloma diagnosis), where the monoclonal light chains are deposited in various parts of the body instead of being cleared by the kidneys. These deposits can cause organ damage, etc.
No.
Light chain escape is by definition a phenomenon that can occur post-treatment, where the body secretes monoclonal light chains at a rate greater than the corresponding intact monoclonal immunoglobulin (i.e. M-spike) rate. It can occur in myeloma patients.
Light chain deposition disease (LCDD) is actually a disease (as opposed to a phenomenon) that is distinct from myeloma (but often is accompanied by a myeloma diagnosis), where the monoclonal light chains are deposited in various parts of the body instead of being cleared by the kidneys. These deposits can cause organ damage, etc.
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Multibilly - Name: Multibilly
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: Smoldering, Nov, 2012
Re: Light chain escape vs. light chain deposition disease
Thank you Multibilly.
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JBritt - Name: Jewell
- Who do you know with myeloma?: Me
- When were you/they diagnosed?: October 2015
- Age at diagnosis: 64
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