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Lamda Light Chain elevation initially NOW Kappa Light Chain

by DarnIachino on Thu Apr 08, 2010 2:48 pm

When my husband was first diagnosed with Multiple Myleoma with Plasma Cell Subset his Lamda Light Chain was elevated. Now after all the treatments & stem cell transplant his Kappa Light Chain is starting to rise. His doctor is puzzled with this development. Can anyone explain or tell me what it means?

DarnIachino
Name: Darnell Iachino
Who do you know with myeloma?: husband Ronnie
When were you/they diagnosed?: February 4, 2009
Age at diagnosis: 61
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Re: Lamda Light Chain elevation initially NOW Kappa Light Chain

by Dr. Bijay Nair on Fri Apr 09, 2010 12:27 pm

It is important to know what the lambda to kappa ratio is, if this is close to normal, then it is likely a benign condition. We have seen the light chains rise in response to inflammation, infection, and at times of count recovery following chemotherapy/transplant, they eventually normalize.

Dr. Bijay Nair
Name: Bijay Prabhakaran Nair, M.D.
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