[bluebell]

Re: Kyprolis clinical trial - heart & travel questions

by bluebell on Wed Apr 01, 2015 12:33 am

This is from the drug company's own instructions:

Heart problems: Kyprolis can cause heart problems or worsen pre-existing heart conditions. Death due to cardiac arrest has occurred within a day of Kyprolis administration. You will be closely monitored during treatment.

Eric, you are correct, it would be a good idea for anybody on Kyprolis to be assessed for heart problems.

Bluebell

[Eric Hofacket]

Re: Kyprolis clinical trial - heart & travel questions

by Eric Hofacket on Wed Apr 01, 2015 9:21 am

bluebell,

Is there a internet link to those instructions for Kyprolis from the manufacture?

[Beacon Staff]

Re: Kyprolis clinical trial - heart & travel questions

by Beacon Staff on Wed Apr 01, 2015 9:28 am

Eric,

The information bluebell quoted is from the patient information on the Kyprolis website; see this page:

http://www.kyprolis.com/starting-kyprolis/side-effects

In case you're looking for it, here is a link to the official, FDA-approved prescribing information for Kyprolis:

http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202714lbl.pdf

[Eric Hofacket]

Re: Kyprolis clinical trial - heart & travel questions

by Eric Hofacket on Wed Apr 01, 2015 10:35 am

Thanks,

I am printing the information and will be going over it.

[Fcbno]

Re: Kyprolis clinical trial - heart & travel questions

by Fcbno on Thu Apr 02, 2015 6:36 pm

I have been on maintenance therapies since my SCT 3 years ago. I have what my oncologist called clinically aggressive myeloma. I have had RVD, RPD, and now am on Kyprolis and dex. May have had other things too but can't remember.

I've been on Kyprolis 2 different times. The first when I relapsed from a complete response to SCT in a year while on maintenance therapy, and then after I had gone into remission but relapsed after that when I was on only Revlimid for 6 months. I'm now back on Kyprolis and my markers are going down.

Of all the drugs I've had, it is the easiest on me. The only hard thing is the 2 days in a row of 3-hour i.v.'s. Plus a blood draw on another day. Makes travel hard.

I have found that the 4th day tends to be a down day, especially on the 3rd week. But one day isn't bad. I get blood draws every week.