Could knee joint degeneration / arthritis be due to MGUS / multiple myeloma?
I had thirty years ago what the physician that time said is due to G6PD but my current three hematologists at three different locations (where I live, where I go for treatment, and where I frequently travel for business) say it was MGUS. I have knee joint pain / degeneration of cartilage in both knees. No other joints such as fingers have any problem.
Thank you.
Forums
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MMFeb16,15 - Who do you know with myeloma?: Self
- When were you/they diagnosed?: February 16, 2015
- Age at diagnosis: 66
Re: Knee joint degeneration and MGUS / multiple myeloma
Hello,
Look here:
Jorgensen, C, et al, "Arthritis associated with monoclonal gammapathy: clinical characteristics," British Journal of Rheumatology, March 1996 (abstract, full-text PDF)
Abstract:
"We report nine cases of arthritis associated with a monoclonal gammapathy. Joint involvement was noted simultaneously or after the diagnosis of monoclonal gammapathy was made. The cases had oligoarthritis or polyarthritis mimicking rheumatoid arthritis. However, rheumatoid factor was absent in all patients, and distal interphalangeal joints were involved in two cases and sacroiliitis in one. The plasma cell dyscrasia was a multiple myeloma in two cases and monoclonal gammapathy of undetermined significance in the other patients. The light chain isotype was kappa in eight of our patients. A type I cryoglobulinaemia was associated in four cases; it was detected in the synovial fluid of two of them. We suggest that the occurrence of paraproteinaemia with chronic arthritis is more than a chance association. Moreover, a monoclonal gammapathy should be searched for in patients presenting with atypical seronegative arthritis."
Did you look for your vitamin D?
Johannes
Look here:
Jorgensen, C, et al, "Arthritis associated with monoclonal gammapathy: clinical characteristics," British Journal of Rheumatology, March 1996 (abstract, full-text PDF)
Abstract:
"We report nine cases of arthritis associated with a monoclonal gammapathy. Joint involvement was noted simultaneously or after the diagnosis of monoclonal gammapathy was made. The cases had oligoarthritis or polyarthritis mimicking rheumatoid arthritis. However, rheumatoid factor was absent in all patients, and distal interphalangeal joints were involved in two cases and sacroiliitis in one. The plasma cell dyscrasia was a multiple myeloma in two cases and monoclonal gammapathy of undetermined significance in the other patients. The light chain isotype was kappa in eight of our patients. A type I cryoglobulinaemia was associated in four cases; it was detected in the synovial fluid of two of them. We suggest that the occurrence of paraproteinaemia with chronic arthritis is more than a chance association. Moreover, a monoclonal gammapathy should be searched for in patients presenting with atypical seronegative arthritis."
Did you look for your vitamin D?
Johannes
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Johannes56 - When were you/they diagnosed?: December 2016
- Age at diagnosis: 60
2 posts
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